Table of Contents
To view the fulltext, log-in or choose pay-per-view options:
Get Access

Endocrine and Cognitive Effects of Short-Time Soybean Consumption in Women

Celec P.a, c · Ostatníková D.b · Cagánová M.d · Žuchová S.b · Hodosy J.b, e · Putz Z.g · Bernadič M.a · Kúdela M.f
Institutes of aPathophysiology and bPhysiology, Faculty of Medicine, Departments of cMolecular Biology, dGenetics, eAnimal Physiology and Ethology, and fZoology, Faculty of Natural Sciences, Comenius University, Bratislava, gNational Institute of Endocrinology and Diabetology, L’ubochňa, Slovakia Gynecol Obstet Invest 2005;59:62–66 (DOI:10.1159/000081895)

Abstract

Background: Soy phytoestrogens are known to influence the hormonal status acting as partial estrogen agonists. Soy-derived food supplements are advised for hormone replacement therapy, prevention of atherosclerosis, age-related cognitive decline and even hormone-dependent cancer, although results from clinical studies are controversial. Whether increased soybean intake can affect the endocrine status and cognitive abilities is largely unknown. Aim: To observe the effects of 1 week of increased soybean intake on sex hormone levels and spatial cognitive abilities in women. Subjects and Methods: 16 young healthy female volunteers were asked to eat 900 g of soybeans within 1 week. Salivary testosterone (T), free and total plasma T, salivary and plasma estradiol (E) were measured by radioimmunoassay before and after the study period. Mental rotation (MR) and spatial visualization (SV) psychological tests were done at the days of sampling. Results: Soybean intake increased total plasma T levels (p < 0.02) while decreasing salivary T (p < 0.01) and not altering free plasma T levels. Salivary and plasma E levels were not changed. The results of MR and SV tests were improved after the study period. Conclusion: Short-time increased soybean intake alters the level of total plasma and salivary T and improves spatial cognition in women. Whether this effect is mediated by modulation of estrogen receptors, changes in sex hormone-binding globulin production or changes in activity of steroid-competent enzymes needs further study.

 

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.


Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50