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Vol. 88, No. 1, 2005
Issue release date: July 2005
Biol Neonate 2005;88:42–45
(DOI:10.1159/000084457)

Prediction of Preterm Delivery by Sonographic Estimation of Cervical Length

Botsis D. · Papagianni V. · Vitoratos N. · Makrakis E. · Aravantinos L. · Creatsas G.
2nd Department of Obstetrics and Gynecology, Aretaieion Hospital, University of Athens, Athens, Greece

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Abstract

Background: Identification of pregnant women presenting with threatened preterm labor who are destined to deliver prematurely would greatly assist planning their management. Objectives: The purpose of the study was to evaluate the ultrasonographic measurement of cervical length as a prognostic factor for predicting preterm birth in cases of threatened preterm labor. Methods: The study included 104 women with singleton pregnancies who presented with threatened preterm labor at 24–36 weeks of gestation. Cervical length at presentation was evaluated by transvaginal ultrasonography. Other potential prognostic factors, such as previous history of preterm labor, smoking, parity and administration of tocolytics were assessed. All women were observed for preterm delivery within 7 days of presentation. Results: The only significant predictor of preterm delivery was cervical length assessed by ultrasound (p < 0.000001, odds ratio 93.3, 95% Cl 10.4–837.1). Conclusions: Cervical length assessed by transvaginal ultrasonography in women presenting with threatened preterm labor is a powerful predictive tool for progression to preterm delivery.



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References

  1. Gyetuai K, Hannah M, Hodnett E, Ohlsson A: Tocolytics for preterm labor: A systematic review. Obstet Gynecol 1999;94:869–877.
  2. King JF, Grant A, Kerse M, Chalmers I: Beta mimetics in preterm labor: An overview of the randomized controlled trials. Br J Obstet Gynaecol 1998;95:211–222.

    External Resources

  3. Tsoi E, Akmal S, Rame S, Otigbah C, Nicolaides K: Ultrasound assessment of cervical length in threatened preterm labor. Ultr Obstet Gynecol 2003;21:552–555.
  4. Andres RL, Day MC: Perinatal complications associated with maternal tobacco use. Semin Neonatol 2000;5:231–241.
  5. Burguet A, Kaminski M, Abraham-Lerat L, Schaal JP, Cambonie G, Fresson J, Grandjean H, Truffert P, Marpeau L, Voyer M, Roze JC, Treisser A, Larroque B: The complex relationship between smoking in pregnancy and very preterm delivery: Results of the Epipage study. Br J Obstet Gynaecol 2004;111:258–265.
  6. Savitz DA, Dole N, Terry JW Jr, Zhou H, Thorp JM Jr: Smoking and pregnancy outcome among African-American and white women in central North Carolina. Epidemiology 2001;12:636–642.
  7. Kolas T, Nakling J, Salvesen KA: Smoking during pregnancy increases the risk of preterm births among parous women. Acta Obstet Gynecol Scand 2000;79:644–648.
  8. Tarter JG, Khoury A, Barton JR, Jacques DL, Sibai BM: Demographic and obstetric factors influencing pregnancy outcome in twin gestations. Am J Obstet Gynecol 2002;186:910–912.
  9. Carlini L, Somigliana E, Rossi G, Veglia F, Busacca M, Vignali M: Risk factors for spontaneous preterm birth: A northern Italian multicenter case-control study. Gynecol Obstet Invest 2002;53:174–180.
  10. Cook C-M, Elwood DA: A longitudinal study of the cervix in pregnancy using transvaginal ultrasound. Br J Obstet Gynaecol 1996;103:16–18.
  11. Kushnir O, Vigil DA, Izqierdo L, Schiff M, Curet LB: Vaginal ultrasonographic assessment of cervical length changes during normal pregnancy. Am J Obstet Gynecol 1990;162:991–993.
  12. Heath V, Southall T, Souka A, Elisseou A, Nicolaides KH: Cervical length at 23 weeks of gestation: Prediction of spontaneous preterm delivery. Ultrasound Obstet Gynecol 1998;12:312–317.
  13. Cetin M, Cetin A: The role of transvaginal sonography in predicting recurrent preterm labour in patients with intact membranes. Eur J Obstet Gynecol Reprod Biol 1997;74:7–11.
  14. Hasegawa I, Tanaka K, Takahashi K, Tanaka K, Aoki K, Torri Y, Okai T, Saji F, Takahashi T, Saro K, Fujimira M, Ogawa Y: Transvaginal ultasonographic cervical assessment for the prediction of preterm delivery. J Matern Fetal Med 1996;5:305–309.
  15. Murakawa H, Utumi T, Hasegawa I, Tanaka K, Fuzimori R: Evaluation of threatened preterm delivery by transvaginal ultrasonographic measurement of cervical length. Obstet Gynecol 1993;82:829–832.
  16. Ams J, Goldenberg RL, Meis PJ, Mercer BM, Moawad A, Das A, Thom E, McNellis D, Copper RL, Johnson F, Roberts JM: The length of the cervix and the risk of spontaneous premature delivery. National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network. N Eng J Med 1996;334:567–572.
  17. Timor-Tritsch I, Boozarjomehri E, Masakowaski Y, Monteagudo A, Chao CR: Can a ‘snapshot’ sagittal view of the cervix by transvaginal sonography predict active preterm labour? Am J Obstet Gynecol 1996;174:990–995.
  18. Hassan SS, Romero R, Berry SM, Dang K, Blakwell C, Treadwell MC, Wafe HM: Patients with an ultrasonographic cervical length <or = 15 mm have nearly a 50% risk of early spontaneous preterm delivery. Am J Obstet Gynecol 2000;182:1458–1467.
  19. Honest H, Bachmann L, Gupta JK, Kleinjnen J, Khank S: Accuracy of cervicovaginal fetal fibronectin tests in predicting risk of spontaneous preterm birth: systematic review. BMJ 2002;325:301–304.
  20. Makrakis E, Grigoriou O, Kouskouni E, Vitoratos N, Salamalekis E, Chatzoudi E, Creatsas GL: Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinases-1 in plasma/serum and urine of women during term and threatened preterm labor: A clinical approach. J Mat Fet Neonat Med 2003;14:1–6.


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