Herbal medicine has long been used to treat neural symptoms. Although the precise mechanisms of action of herbal drugs have yet to be determined, some of them have been shown to exert anti-inflammatory and/or anti-oxidant effects in a variety of peripheral systems. Now, as increasing evidence indicates that neuroglia-derived chronic inflammatory responses play a pathological role in the central nervous system, anti-inflammatory herbal medicine and its constituents are being proved to be a potent neuroprotector against various brain pathologies. Structural diversity of medicinal herbs makes them valuable source of novel lead compounds against therapeutic targets that are newly discovered by genomics, proteomics, and high-throughput screening.
© 2005 S. Karger AG, Basel
- Neurodegenerative disease
- Central nervous system
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Department of Pharmacology, Pain and Neural Injury Research Center
Kyungpook National University School of Medicine
101 Dong-In, Joong-Gu, Daegu, 700-422 (Korea)
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Received: July 28, 2004
Accepted after revision: September 20, 2004
Number of Print Pages : 11
Number of Figures : 4, Number of Tables : 1, Number of References : 96
Vol. 14, No. 1-2, Year 2005 (Cover Date: Released June 2005)
Journal Editor: Ip, N.Y. (Hong Kong)
ISSN: 1424–862X (print), 1424–8638 (Online)
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