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Table of Contents
Vol. 14, Suppl. 1, 2005
Issue release date: July 2005
Section title: Review
Open Access Gateway
Med Princ Pract 2005;14:2–14
(DOI:10.1159/000086179)

Megaloblastosis: From Morphos to Molecules

Das K.C.a · Das M.b · Mohanty D.b · Jadaon M.M.a · Gupta A.a · Marouf R.a · Easow S.K.a
aHematology Unit, Department of Pathology, Faculty of Medicine, Kuwait University, Kuwait; bInstitute of Immunohematology, Mumbai, India
email Corresponding Author

Dr. K.C. Das

Hematology Unit, Department of Pathology, Faculty of Medicine, Kuwait University

PO Box 24923, 13110 Safat (Kuwait)

Tel. +965 531 9476, Fax +965 533 8905

E-Mail drkcdas@hotmail.com, kshitish@hsc.edu.kw


References

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  10. Das KC, Hoffbrand AV: Lymphocyte transformation in megaloblastic anaemias. Morphology and DNA synthesis. Br J Haematol 1970;19:459–468.
  11. Das KC, Herbert V: The lymphocyte as a marker of past nutritional status. Persistence of abnormal lymphocyte deoxyuridine (dU) suppression test and chromosomes in patients with past deficiency of folate and vitamin B12. Br J Haematol 1978;38:219–223.
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  17. Das KC, Manusselis C, Herbert V: In vitro DNA synthesis by bone marrow cells and PHA-stimulated lymphocytes. Suppression by non radioactive thymidine of the incorporation of 3H-deoxyuridine into DNA: Enhancement of incorporation when inadequate vitamin B12 and folate is corrected. Br J Haematol 1980;44:51–63.
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  32. Zhao J: Coordination of DNA synthesis and histone gene expression during normal cell cycle progression and after DNA damage. Cell Cycle 2004;3:695–697.
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  34. Wang C, Fu M, Pestell RG: Histone acetylation/deacetylation as a regulator of cell cycle gene expression. Methods Mol Biol 2004;241:207–216.
  35. McLaughlin F, La Thangue NB: Histone deacetylase inhibitors open new doors in cancer therapy. Biochem Pharmacol 2004;68:1139–1144.
  36. Ingram CF, Davidoff AN, Marais F, Sherman GG, Mendelow BV: Evaluation of DNA analysis for evidence of apoptosis in megaloblastic anaemia. Br J Haematol 1997;96:576–583.
  37. Koury MJ, Price JO, Hicks GG: Apoptosis in megaloblastic anemia occurs during DNA synthesis p53-independent, nucleoside-reversible mechanism. Blood 2000;96:3249–3255.
  38. Gu L, Wu J, Qiu L, Jennings CD, Li GM: Involvement of DNA mismatch repair infolate deficiency-induced apoptosis small star, filled. J Nutr Biochem 2002;13:355–363.
  39. Li GM, Presnell SR, Gu I: Folate deficiency, mismatch repair-independent apoptosis and human disease. J Nutr Biochem 2003;14:568–575.
  40. Das KC, Easow SK, Jadaon M, Das M, Mohanty D: The development of megaloblastosis is a species-restricted phenomenon. 9th Annu Health Sci Poster Conf, Kuwait, April 19–21, 2004, p 284.