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Table of Contents
Vol. 5, No. 6, 2005
Issue release date: 2005
Section title: Original Paper
Pancreatology 2005;5:547–552
(DOI:10.1159/000087496)

Duodenopancreatectomy versus Duodenum-Preserving Pancreatic Head Excision for Chronic Pancreatitis

Belina F. · Fronek J. · Ryska M.
Department of Surgery, Central Military Hospital, Prague, Czech Republic

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 12/3/2003
Accepted: 2/28/2004
Published online: 9/28/2005

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 6

ISSN: 1424-3903 (Print)
eISSN: 1424-3911 (Online)

For additional information: http://www.karger.com/PAN

Abstract

Background: The aim of this study was to compare two surgical procedures in the treatment for chronic pancreatitis (CP): pancreatoduodenectomy resection (classical Whipple – PD procedure, or pylorus-preserving – PPPD) to duodenum-preserving pancreatic head excision with longitudinal pancreatojejunoanastomosis (DPPHE/PJA), to define the advantages of each procedure with regard to postoperative complications, pain relief, and the quality of life. Material and Method: 104 consecutive patients were included into this study. Duodenopancreatectomy was chosen when the head pancreatic mass was present or pancreatic cancer could not be ruled out (48 patients); otherwise DPPHE/PJA was performed (56 patients). Quality of life was measured prospectively on two occasions, before the procedure and during follow-up (median 39 months after surgery) using the European Organization for Research and Treatment of Cancer (EORTC) Quality-of-Life Questionnaire (QLQ-C30). The test was re-evaluated for patients suffering from CP. Pain intensity was quantified using a specially designed pain score. Early postoperative morbidity and mortality were assessed and evaluated in both groups of patients. Results: Total pain score decreased significantly after surgery in both groups of patients. During the follow-up period, the global quality of life improved by 30.4% in the DPPHE/PJA group, and by 23.2% in the PD/PPPD group. Postoperative morbidity and mortality were higher in the resection group, but the differences were not significant. Conclusions: Both surgical procedures led to significant improvement in the quality of life and pain relief after surgery for CP. The EORTC QLQ-C30 was found to be a valid and readily available test for quality-of-life assessment in patients with CP.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 12/3/2003
Accepted: 2/28/2004
Published online: 9/28/2005

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 6

ISSN: 1424-3903 (Print)
eISSN: 1424-3911 (Online)

For additional information: http://www.karger.com/PAN


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

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    External Resources

  16. Huang JJ, Yeo CJ, Sohn TA, Lillemoe KD, et al: Quality of life and outcomes after pancreaticoduodenectomy. Ann Surg 2000;231:890–898.
  17. Fronek J, Ryska M, Belina F, et al: Quality of life in chronic pancreatitis – results after duodenum-preserving resection of the head of the pancreas (abstract). International 4th Congress of the European Chapter of the International Hepato-Pancreato-Biliary Association, Amsterdam 2001, pp 27–30.
  18. Witzigmann H, Max D, Uhlmann D, et al: Quality of life in chronic pancreatitis: a prospective trial comparing classical Whipple procedure and duodenum-preserving pancreatic head resection. J Gastrointestinal 2002;S6:173–180.

    External Resources