Effect of Sucrose Concentration on Dental Biofilm Formed in situ and on Enamel DemineralizationAires C.P.a · Tabchoury C.P.M.a · Del Bel Cury A.A.a · Koo H.b · Cury J.A.a
aFaculty of Dentistry of Piracicaba, UNICAMP, Piracicaba, Brazil; bEastman Department of Dentistry and Center for Oral Biology, University of Rochester, Rochester, N.Y., USA Caries Res 2006;40:28–32 (DOI:10.1159/000088902)
The relationship between sucrose concentration and cariogenic potential was studied in situ. Adult volunteers wore intraoral palatal appliances containing human dental enamel blocks, which were extraorally submitted 8 times a day for 14 days, to the treatments: deionized distilled water and sucrose solutions from 1 to 40%. The biofilm formed was analyzed with respect to acidogenicity and biochemical composition; enamel demineralization was evaluated by microhardness. The results showed that 1% sucrose is less cariogenic than 5% or higher concentrations, although sucrose solution at 40% was still able to increase the concentration of insoluble polysaccharide in the biofilm formed. The findings suggest that the threshold of sucrose solution concentration for the formation of a cariogenic biofilm is 5%, which provided the same cariogenic potential as that observed for 10 and 20% sucrose solution.
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