Journal Mobile Options
Table of Contents
Vol. 40, No. 1, 2006
Issue release date: December 2005

The Effect of Adding Calcium Lactate to Xylitol Chewing Gum on Remineralization of Enamel Lesions

Suda R. · Suzuki T. · Takiguchi R. · Egawa K. · Sano T. · Hasegawa K.
To view the fulltext, log in and/or choose pay-per-view option

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Abstract

The purpose of the study was to determine whether adding calcium lactate to chewing gum containing xylitol enhances remineralization of enamel surfaces using an early caries lesion model. Enamel slabs were cut from human extracted sound teeth and artificial subsurface lesions created within each. Half the enamel slabs were used as controls and stored in a humidifier while half were mounted into oral appliances worn by 10 volunteers (22–27 years old, 2 males and 8 females) in a three-leg trial, during which they wore the appliance without chewing gum, chewed gum containing xylitol + calcium lactate or chewed gum containing only xylitol 4 times a day for 2 weeks. Calcium concentrations in the enamel surfaces of control and test slabs were measured by X-ray spectrometry and degrees of remineralization were calculated. The mean degree of remineralization was greater after chewing xylitol-Ca gum (0.46 ± 0.10) than after no gum (0.16 ± 0.14) or after chewing xylitol gum (0.33 ± 0.10) (p < 0.01). In conclusion, chewing gum containing xylitol + calcium lactate could enhance remineralization of enamel surface compared to chewing gum containing only xylitol or no gum chewing.



Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Angyal SJ, Millis JA: Complexes of carbohydrates with metal cations. Aust J Chem 1979;32:1993–2001.
  2. Grøn P: Remineralization of enamel lesions in vivo. Oral Sci Rev 1973;3:84–99.

    External Resources

  3. Kieboom APG, Buurmans HMA, van Leeuwen LK, van Benschop HJ: Stability constants of (hydroxy)carbozylate- and aldol-Ca (II) complexes. J R Neth Chem Soc 1979;98:393–395.
  4. Lagerlöf F, Oliveby A: Caries-protective factors in saliva. Adv Dent Res 1994;8:229–238.
  5. Scheinin A, Söderling E, Scheinin U, Glass RL, Kallio ML: Xylitol-induced changes of enamel microhardness paralleled by microradiographic observations. Acta Odontol Scand 1993;51:241–246.
  6. Smits MT, Arends J: Influence of extraoral xylitol and sucrose dippings on enamel demineralization in vivo. Caries Res 1988;22:160–165.
  7. Söderling E, Isokangas P, Tenovuo J, Mustakallio S, Makinen KK: Long-term xylitol consumption and mutans streptococci in plaque and saliva. Caries Res 1991;25:153–157.
  8. Trahan L: Xylitol: A review of its action on mutans streptococci and dental plaque – its clinical significance. Int Dent J 1995;45:77–92.


Pay-per-View Options
Direct payment This item at the regular price: USD 33.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 23.00