Objective: To determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains among clinical isolates collected from the 4 tertiary hospitals in Makkah, Saudi Arabia, and to test the antimicrobial susceptibility patterns of S. aureus isolates against 9 antimicrobial agents. Materials and Methods: A total of 512 S. aureus clinical isolates were collected during a period of 1 year starting in April 2003 in Al-Noor, King Abdul-Aziz, Hera and King Faisal Hospitals, Makkah, Saudi Arabia. The sensitivity patterns of these isolates were determined using the Kirby-Bauer disk diffusion method. Results: The prevalence of MRSA among S. aureus isolates was 38.9% (199/512). Among 199 MRSA isolates, 78.8% showed multidrug resistance to erythromycin, gentamicin and oxytetracycline. Conclusion: The rate of MRSA resistance in this study was much higher than what had been reported in other areas of Saudi Arabia emphasizing the need for local or country-based surveillance to characterize and monitor MRSA and to develop strategies that will improve MRSA treatment and control.
© 2006 S. Karger AG, Basel
- Methicillin-resistant Staphylococcus aureus
- Antimicrobial resistance
- Nosocomial infection
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Dr. Aiman M. Momenah
PO Box 6630
Makkah (Saudi Arabia)
Tel. +966 503501449, Fax +966 25270000, ext. 7111
Received: December 12, 2004
Revised: June 8, 2005
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 2, Number of References : 25
Medical Principles and Practice (International Journal of the Kuwait University Health Sciences Centre)
Vol. 15, No. 1, Year 2006 (Cover Date: December 2005)
Journal Editor: Al-Zaid, N.S. (Kuwait)
ISSN: 1011–7571 (print), 1423–0151 (Online)
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