Journal Mobile Options
Table of Contents
Vol. 73, No. 1, 2006
Issue release date: April 2006
Digestion 2006;73:1–8
(DOI:10.1159/000090036)

Seasonal Patterns of Hospital Treatment for Inflammatory Bowel Disease in Italy

Soncini M. · Triossi O. · Leo P. · Magni G. · Giglio L.A. · Mosca P.G. · Bertelè A.M. · Pompeo F. · Pietrini L. · Muratori R. · Marone G.P. · Belfiori V. · Sciampa G. · Tanzilli A. · Azzola E. · Ferraris L. · Grasso T. · Caruso S. · Bonecco S. · Casanova B. · Brambilla G. · Frulloni L. · D’Offizi V.
Departments of Gastroenterology,aS. Carlo Borromeo Hospital, Milan, bS. Maria delle Croci Hospital, Ravenna, cAnnunziata Hospital, Cosenza, dS. Camillo Forlanini Hospital, Rome, eTorrette Hospital, Ancona, fParma Hospital, Parma, gRegina Apostolorum Hospital, Albano Laziale, hUniversity of Bari, Bari, iS. Orsola Malpighi Hospital, Bologna, jAscalesi Hospital, Naples, kTorrette Hospital, Ancona, lS. Pio da Pietrelcina Hospital, Vasto, mDel Prete Hospital, Pontecorvo, nSanta Corona Hospital, Pietra Ligure, oS. Antonio Abate Hospital, Gallarate, pS. Maurizio Hospital, Bolzano, qLegnano Hospital, Legnano, rVarese Hospital, Varese, sCareggi Hospital, Florence, tCrema Hospital, Crema, uG.B. Rossi Hospital, Verona, vS. Luca Hospital, Rome, and wQBGROUP spa, Padua, Italy

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Abstract

Aim: It is still debated whether clinical flare-ups of chronic inflammatory bowel disease follow a seasonal pattern, and the various reports are based on general practitioners’ records or hospital discharge charts. There are, however, no specific figures for treatment in hospital gastroenterology units, which serve as a reference point for these disorders. This study was therefore designed to investigate whether there is a seasonal pattern in admissions for inflammatory intestinal disease in Italy, differing from what is generally known about gastrointestinal pathologies, since there are no nation-wide figures on the subject. Methods: The RING (Ricerca Informatizzata in Gastroenterologia) project is an observational study collecting hospital discharge forms from 22 centers in Italy. Results: From winter 2000 to autumn 2003, the 22 gastroenterology units participating in the RING project discharged 32,357 patients following ordinary hospital admissions. Of these, 2,856 (8.8%) had a main diagnosis of inflammatory bowel disease: 1,541 Crohn’s disease, and 1,315 ulcerative colitis. No seasonal patterns were detected for either category, or when the analysis was done by age, sex and site of disease. Conclusions: The most serious flare-ups of inflammatory bowel disease, i.e. those requiring routine hospital treatment, do not appear to follow any seasonal pattern, regardless of the site of the disease or the patient’s age or sex.



Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Myszor M, Calam J: Seasonality of ulcerative colitis. Lancet 1984;2:522–523.
  2. Sellu DP: Seasonal variation in onset of exacerbations of ulcerative proctocolitis. J R Coll Surg Edinb 1986;31:158–160.
  3. Riley SA, Mani V, Goodman MJ, Lucas S: Why do patients with ulcerative colitis relapse? Gut 1990;31:179–183.
  4. Kangro HO, Chong SK, Hardiman A, Heath RB, Walker-Smith JA: A prospective study of viral and mycoplasma infections in chronic inflammatory bowel disease. Gastroenterology 1990;98:549–553.
  5. Don BAC, Goldacre MJ: Absence of seasonality in emergency hospital admissions for inflammatory bowel disease. Lancet 1984;ii:1156–1157.
  6. Tysk C, Jarnerot G: Seasonal variation in exacerbations of ulcerative colitis. Scand J Gastroenterol 1993;28:95–96.
  7. Sonnenberg A, Jacobsen SJ, Wasserman IH: Periodicity of hospital admissions for inflammatory bowel disease. Am J Gastroenterol 1994;89:847–851.
  8. Zeng L, Anderson FH: Seasonal changes in the exacerbations of Crohn’s disease. Scand J Gastroenterol 1996;31:79–82.
  9. Moum R, Aadland F, Ekbom A, Vatn MH: Seasonal variations in the onset of ulcerative colitis. Gut 1996;38:376–378.
  10. Lewis JD, Aberra FN, Lichtenstein GR, Bilker WB, Brensinger C, Strom BL: Seasonal variation in flares of inflammatory bowel disease. Gastroenterology 2004;126:665–673.
  11. Karamanolis DG, Delis KC, Papatheodoris GV, Kalafatis E, Paspatis G, Xourgias VC: Seasonal variation in exacerbations of ulcerative colitis. Hepatogastroenterology 1997;44:1334–1338.
  12. Vergara M, Fraga X, Casellas F, Bermejo B, Malagelada JR: Seasonal influence in exacerbations of inflammatory bowel disease. Rev Esp Enferm Dig 1997;89:357–366.
  13. Soncini M, Triossi O, Leo P, Magni G: Inflammatory bowel disease and hospital treatment in Italy: The RING multi-center study. Aliment Pharmacol Ther 2004;19:63–68.
  14. Ministero della Sanità: Classificazione degli interventi chirurgici e delle procedure diagnostico-terapeutiche. Roma, Istituto Poligrafico Zecca dello Stato,1997.
  15. Best WR, Becktel JM, Singleton JW, Kern F Jr: Development of a Crohn’s disease activity index. National Cooperative Crohn’s Disease Study. Gastroenterology 1976;70:439–444.
  16. Truelove SC, Witts LJ: Cortisone in ulcerative colitis, final report on a therapeutic trial. Br Med J 1955;ii:1041–1048.


Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50