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Table of Contents
Vol. 22, No. 5, 2005
Issue release date: February 2006
Section title: Short Report
Dig Surg 2005;22:371–374
(DOI:10.1159/000090996)

Primary Squamous Cell Carcinoma of the Colon Associated with Hypercalcemia and Hyperleukocytosis

Report of a Case

Yitta S. · Liang M.K. · Berman R. · Carter J.J. · Yee H.T. · Marks J.L.
Department of Surgery, New York University School of Medicine, Bellevue Hospital Center, New York, N.Y., USA

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Article / Publication Details

First-Page Preview
Abstract of Short Report

Received: 6/20/2005
Accepted: 8/22/2005
Published online: 2/23/2006

Number of Print Pages: 4
Number of Figures: 5
Number of Tables: 0

ISSN: 0253-4886 (Print)
eISSN: 1421-9883 (Online)

For additional information: http://www.karger.com/DSU

Abstract

Background/Aims: Squamous cell carcinoma of the colon is a rare entity. We report a case of a patient who presented with a perforated squamous cell carcinoma of the sigmoid colon. Results: A 45-year-old female presented with a 2-month history of worsening abdominal pain, bloody diarrhea, and vomiting. She underwent an exploratory laparotomy and was found to have keratinizing squamous cell carcinoma of the sigmoid colon that had perforated forming multiple abscess cavities. The postoperative course was complicated by hypercalcemia and persistent hyperleukocytosis, ultimately resulting in the patient’s death. Conclusions: We present the second reported case of squamous cell carcinoma of the colon associated with hypercalcemia and the first reported case of associated hyperleukocytosis.


Article / Publication Details

First-Page Preview
Abstract of Short Report

Received: 6/20/2005
Accepted: 8/22/2005
Published online: 2/23/2006

Number of Print Pages: 4
Number of Figures: 5
Number of Tables: 0

ISSN: 0253-4886 (Print)
eISSN: 1421-9883 (Online)

For additional information: http://www.karger.com/DSU


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Juturi JV, Francis B, Koontz PW, Wilkes JD: Squamous cell carcinoma of the colon responsive to combination chemotherapy: report of two cases and review of the literature. Dis Colon Rectum 1999;42:102–109.
  2. Yoshida J, Tohma, H, Nagata T, Okuzono Y, Takahashi M: Squamous cell carcinoma of the splenic flexure of the colon: report of a case. Jpn J Surg 1994;24:75–79.
  3. Crissman JD: Adenosquamous and squamous cell carcinoma of the colon. Am J Surg Pathol 1978;2:47–54.
  4. Frizelle FA, Hobday KS, Batts KP, Nelson H: Adenosquamous and squamous carcinoma of the colon and upper rectum: a clinical and histopathologic study. Dis Colon Rectum 2001;44:341–346.
  5. Audeau A, Han HW, Johnston MJ, Whitehead MW, Frizelle FA: Does human papilloma virus have a role in squamous cell carcinoma of the colon and upper rectum? Eur J Surg Oncol 2002;6:657–660.
  6. Delellis RA, Xia L: Paraneoplastic andocrine syndromes: a review. Endocr Pathol 2003;14:303–318.
  7. Thompson JT, Paschold EH, Levine EA: Paraneoplastic hypercalcemia in a patient with adenosquamous cancer of the colon. Am Surg 2001;67:585–588.
  8. Clifford ML: Excess leukocytosis (leukemoid reactions) associated with malignant diseases. South Med J 1985;78:1475–1482.

    External Resources

  9. Eichenhorn MS, Van Slyck EJ: Marked mature neutrophilic leukocytosis: a leukemoid variant associated with malignancy. Am J Med Sci 1982;284:32–36.
  10. Copur S, Ledakis P, Novinski D, Mleczko KL, Frankforter S, Bolotn M, Fruehling RM, VanWie E, Norvell M, Muhvic J: Squamous cell carcinoma of the colon with an elevated serum squamous cell carcinoma antigen responding to combination chemotherapy. Clin Colorectal Cancer 2001;1:55–58.