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Bladder Squamous Metaplasia of the Urothelium – Introductory Report

Jurkiewicz B.a · Matuszewski Ł.a · Bokwa T.a · Gut G.b · Rybak D.a
aPediatric Surgery Ward, Warsaw’s Hospital for Children, and bDepartment of Transplantology and Central Tissue Bank Medical Academy, Warsaw, Poland Urol Int 2006;77:46–49 (DOI:10.1159/000092934)


Seven female patients hospitalized in the Surgery Ward of Warsaw’s Hospital for Children are described. Nonspecific abdominal pains, recurrent urinary tract infections, and voiding disorders (difficulty in voiding commencement) were the primary causes of hospitalization. Urodynamics and cystoscopy with a histopathology section of the urothelium achieved the diagnosis of nonkeratizing squamous cell metaplasia of the urothelium. The topic is not new, although the diagnosis is particularly rare in the pediatric patient. Until now, the existing world literature has described only a few cases of this kind of metaplasia in children. These findings may be helpful in differential diagnosis of urinary bladder disease. It is postulated that nonkeratizing squamous cell metaplasia of the urothelium, in the future, may lead to malignant changes in the urothelium. Therefore, the therapeutic process merits close monitoring.


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