Journal Mobile Options
Table of Contents
Vol. 77, No. 1, 2006
Issue release date: July 2006

Bladder Squamous Metaplasia of the Urothelium – Introductory Report

Jurkiewicz B. · Matuszewski Ł. · Bokwa T. · Gut G. · Rybak D.
To view the fulltext, log in and/or choose pay-per-view option

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Abstract

Seven female patients hospitalized in the Surgery Ward of Warsaw’s Hospital for Children are described. Nonspecific abdominal pains, recurrent urinary tract infections, and voiding disorders (difficulty in voiding commencement) were the primary causes of hospitalization. Urodynamics and cystoscopy with a histopathology section of the urothelium achieved the diagnosis of nonkeratizing squamous cell metaplasia of the urothelium. The topic is not new, although the diagnosis is particularly rare in the pediatric patient. Until now, the existing world literature has described only a few cases of this kind of metaplasia in children. These findings may be helpful in differential diagnosis of urinary bladder disease. It is postulated that nonkeratizing squamous cell metaplasia of the urothelium, in the future, may lead to malignant changes in the urothelium. Therefore, the therapeutic process merits close monitoring.



Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Cotran R, Kumar V, Robbins S: Robbins Pathologic Basis of Disease, ed 5. Philadelphia, Saunders, 1994, pp 48–49.
  2. Capozza N, Collura G, Nappo S, de Dominicis M, Francalanci P, Caione P: Cystitis glandularis in children. BJU Int 2005;95:411–413.
  3. Grunebaum M, Varsano I: Multiple bladder filling defects in children with cystitis. Pediatr Radiol 1976;4:93–95.
  4. Tramoyeres Galvan A, Canovas Ivorra JA, Sanchez Ballester F, De la Torre Abril L, Lopez Alcina E, Navalon Verdejo P, Zaragoza Orts J: Bladder squamous metaplasia: report of one case and bibliographic review (in Spanish). Arch Esp Urol 2005;58:74–76.
  5. Youngson GG: Squamous metaplasia complicating a müllerian duct remnant. Br J Urol 1990;65:211–212.
  6. Youngson GG, Galley R, Johnston PW: Columnar metaplasia complicating neurogenic bladder in a child. Br J Urol 1992;70:98–99.
  7. Ankem MK, Grotas AB, Shurtleff B, DiPiazza D, Barnard N, Barone JG: Nonkeratinizing squamous metaplasia of the bladder in children. Infect Urol 2002;15:22–25.
  8. Andriole V: When to do culture in urinary tract infections. Int J Antimicrob Agents 1999;11:253–255.
  9. Khan MS, Thornhill A, Gaffney E, Loftus B, Butler M: Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years’ experience. Eur Urol 2002;42:469–474.
  10. Burin GJ, Gibb HJ, Hill RN: Human bladder cancer: evidence for a potential irritation-induced mechanism. Food Chem Toxicol 1995;33, 9:785–795.
  11. Montironi R, Mazzucchelli R: Preneoplastic lesions and conditions of the urinary bladder. EAU Update Series 2003;1:53–63.

    External Resources

  12. Oyasu R: Epithelial tumors of the lower urinary tract in humans and rodents. Food Chem Toxicol 1995;33:747–755.


Pay-per-View Options
Direct payment This item at the regular price: USD 33.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 23.00