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Table of Contents
Vol. 213, No. 2, 2006
Issue release date: August 2006
Section title: Case Report
Dermatology 2006;213:159–162
(DOI:10.1159/000093859)

Acquired Melanocytic Naevus in Childhood Vulval Pemphigoid

Lebeau S. · Braun R.P. · Masouyé I. · Perrinaud A. · Harms M. · Borradori L.
Clinic of Dermatology, University Hospital, Geneva, Switzerland

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 12/1/2005
Accepted: 2/25/2006
Published online: 8/28/2006

Number of Print Pages: 4
Number of Figures: 3
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Background: Eruptive epidermolysis bullosa (EB) naevi comprise a subset of melanocytic naevi with atypical features that characteristically occur in areas of former blistering in patients suffering from hereditary EB. Observation: The case is reported of a girl who presented with pruritus, blistering and erosions of the vulval region. Clinical and immunopathological features were consistent with the diagnosis of childhood vulval pemphigoid. In the course of the disease, she developed an atypical melanocytic naevus on the left labium at a site of former blistering. Although its clinical and dermoscopic features resembled malignant melanoma, the lesion completely regressed clinically during the 24-month follow-up. Conclusion: This is the first report describing the development of a melanocytic naevus at sites of blistering in an auto-immune subepidermal blistering disease in childhood. Our observation extends the spectrum of disorders, in addition to the group of congenital EB, in which ‘eruptive’ atypical melanocytic naevi may occur. Knowledge of this complication is important for appropriate management and follow-up and to avoid radical surgery.


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 12/1/2005
Accepted: 2/25/2006
Published online: 8/28/2006

Number of Print Pages: 4
Number of Figures: 3
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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