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Table of Contents
Vol. 78, No. 3, 2007
Issue release date: April 2007
Section title: Original Paper
Urol Int 2007;78:260–263
(DOI:10.1159/000099349)

Is Second-Line Enuretic Alarm Therapy after Unsuccessful Pharmacotherapy Superior to First-Line Therapy in the Treatment of Monosymptomatic Nocturnal Enuresis?

Tuygun C. · Eroglu M. · Bakirtas H. · Gucuk A. · Zengin K. · Imamoglu A.
Department of Urology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 5/24/2006
Accepted: 7/21/2006
Published online: 4/4/2007

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 3

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: http://www.karger.com/UIN

Abstract

Introduction: We aimed at comparing the success rates of primary enuretic alarm therapy with those of secondary alarm therapy after failed pharmacotherapy in the treatment of monosymptomatic nocturnal enuresis (MNE). Patients and Methods: We randomly applied enuretic alarm therapy in 35 MNE patients (group 1) and desmopressin therapy in 49 MNE patients (group 2). The success and rebound rates after 3 and 6 months were determined. We also applied enuretic alarm therapy as a secondary treatment in 19 group 2 patients with complete rebound after 6 months (group 3). The success rates of patients who have received primary and secondary enuretic alarm therapy were compared. Results: The success rates for groups 1 and 2 were 82.65 and 81.63%, respectively (p = 0.885), at 3 months and 54.28 and 26.53%, respectively (p = 0.007), at 6 months. The success rates in group 3 were 84.21 and 52.63%, respectively, at 3 and 6 months. When these success rates were compared between groups 1 and 3, no statistically significant difference was found (p = 1.000). Conclusion: Prior pharmacotherapy did not increase success rates of alarm therapy in our MNE patients.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 5/24/2006
Accepted: 7/21/2006
Published online: 4/4/2007

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 3

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: http://www.karger.com/UIN


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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