Journal Mobile Options
Table of Contents
Vol. 214, No. 3, 2007
Issue release date: March 2007

Multicentric Reticulohistiocytosis-Mimicking Dermatomyositis

Case Report and Review of the Literature

Muñoz-Santos C. · Sàbat M. · Sáez A. · Gratacós J. · Luelmo J.
To view the fulltext, log in and/or choose pay-per-view option

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Abstract

Multicentric reticulohistiocytosis is a rare disorder of unknown etiology, characterized by skin and mucosal papulonodular eruptions and destructive polyarthritis. Histopathological study of these lesions shows a nodular infiltrate composed of histiocytes and multinucleated giant cells, with an eosinophilic, granular, ‘ground-glass’ cytoplasm. We report a case of multicentric reticulohistiocytosis with skin lesions mimicking dermatomyositis and we also review previously reported cases describing such a clinical situation. Our case further emphasizes that multicentric reticulohistiocytosis can mimic clinical features of dermatomyositis. A macular or patch-like erythema in a photodistributed fashion, in addition to other clinical manifestations, can be mistaken for dermatomyositis. However, skin biopsies from these areas may early differentiate both conditions with different treatment options and morbidity.



Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Pei Lin Ng P, Lin Gan S: Koebner phenomenon in dermatomyositis. Dermatology 2006;213:249–250.
  2. Du Vivier A: Atlas of Clinical Dermatology, ed 3. Edinburgh, Churchill Livingstone, 2002.
  3. Gao IK, Gorozny JJ, Weyand CM: Ten-year follow-up of a patient with multicentric reticulohistiocytosis associated with myopathy. Scand J Rheumatol 1990;19:437–441.
  4. Gajic-Veljic M, Nikolic MM, Bukilica M, Bonaci-Nikolic B: Multicentric reticulohistiocytosis. A case with minimal articular changes. J Eur Acad Dermatol Venereol 2006;20:108–110.
  5. McIlwain KL, DiCarlo JB, Miller SB, Lim S: Multicentric reticulohistiocytosis with prominent cutaneous lesions and proximal muscle weakness masquerading as dermatomyositis. J Rheumatol 2005;32:193–194.
  6. Hsiung SH, Chan EF, Elenitsas R, Kolasinski SL, Schumacher HR, Werth VP: Multicentric reticulohistiocytosis presenting with clinical features of dermatomyositis. J Am Acad Dermatol 2003;48(suppl):S11–S14.

    External Resources

  7. Tait TJ, Bird HA, Ford GP: Multicentric reticulohistiocytosis: presentation with the cutaneous features of dermatomyositis. Br J Rheumatol 1994;33:100–101.
  8. Hsu S, Ward SB, Le EH, Lee JB: Multicentric reticulohistiocytosis with neurofibroma-like nodules. J Am Acad Dermatol 2001;44(suppl):373–375.

    External Resources

  9. Kenik JG, Fok F, Huerter CJ, Hurley JA, Stanosheck JF: Multicentric reticulohistiocytosis in a patient with malignant melanoma: a response to cyclophosphamide and a unique cutaneous feature. Arthritis Rheum 1990;33:1047–1051.
  10. Sachs RN, Garnier J, Daupleix D, Kemeny JL, Amouroux J, Lanfranchi J: Réticulo-histiocytose multicentrique. Fistulisation cutanée. Nouv Presse Med 1982;11:1497.
  11. Lehrer A, Bergero A, Soriano F: Reticulohistiocytosis multicentrica. Rev Argent Dermatol 1984;65:215–219.
  12. Flaming JA, Weigand DA: Unusual case of multicentric reticulohistiocytosis. Int J Dermatol 1993;32:125–127.
  13. Rendall JR, Vanhegan RI, Robb-Smith AH, Bowers RE, Ryan TJ, Vickers HR: Atypical multicentric reticulohistiocytosis with paraproteinemia. Arch Dermatol 1977;113:1576–1582.
  14. Giam YC, Ong BH: Multicentric reticulohistiocytosis. Ann Acad Med Singapore 1988;17:548–550.
  15. Conaghan P, Miller M, Dowling JP, Cowen P, Littlejohn G: A unique presentation of multicentric reticulohistiocytosis in pregnancy. Arthritis Rheum 1993;36:269–272.
  16. Gold KD, Sharp JT, Estrada RG, Duffy J, Person DA: Relationship between multicentric reticulohistiocytosis and tuberculosis. JAMA 1977;237:2213–2214.
  17. Ginsburg WW, O’Duffy JD: Multicentric reticulohistiocytosis; in Kelly WN, Harris ED Jr, Rudge S, et al (eds): Textbook of Rheumatology. Philadelphia, Saunders, 1985, pp 1502–1505.
  18. Barrow MV, Holubar K: Multicentric reticulohistiocytosis. A review of 33 patients. Medicine (Baltimore) 1969;48:287–305.
  19. Campbell DA, Edwards NL: Multicentric reticulohistiocytosis: systemic macrophage disorder. Baillieres Clin Rheumatol 1991;5:301–319.
  20. Catterall MD: Multicentric reticulohistiocytosis: a review of eight cases. Clin Exp Dermatol 1980;5:267–279.
  21. Luz FB, Gaspar AP, Kalil-Gaspar N, Ramos-e-Silva M: Multicentric reticulohistiocytosis. J Eur Acad Dermatol Venereol 2001;15:524–531.
  22. Trotta F, Castellino G, Lo Monaco A: Multicentric reticulohistiocytosis. Best Pract Res Clin Rheumatol 2004;18:759–772.
  23. Ehrlich GE, Young I, Nosheny SE, Katz WA: Multicentric reticulohistiocytosis (lipoid dermatoarthritis). Am J Med 1972;53:830–840.

    External Resources



Pay-per-View Options
Direct payment This item at the regular price: USD 33.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 23.00