Journal Mobile Options
Table of Contents
Vol. 37, No. 3, 2003
Issue release date: May–June 2003
Caries Res 2003;37:166–171
(DOI:10.1159/000070439)

Effect of Fluoridated Milk on Progression of Root Surface Lesions in vitro under pH Cycling Conditions

Ivancakova R. · Hogan M.M. · Harless J.D. · Wefel J.S.
aDepartment of Dentistry, University Hospital and Medical Faculty of Charles University, HradecKralove, Czech Republic; bDows Institute for Dental Research, College of Dentistry, University of Iowa, IowaCity,Iowa, USA

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Abstract

The aim of this study was to assess the effect of milk with 0, 2.5 or 5 ppm F on progression and remineralization of caries-like root surface lesions using a pH cycling model. The root surface lesions were created utilizing a partially saturated lactic acid buffer at pH 4.6. Longitudinal sections were cut through the lesion and analyzed using polarized light microscopy (PLM) and microradiography (MRG). The sections were then coated with an acid resistant varnish, except the outer natural surface that would be exposed to water, milk or fluoridated milk and cycled in a de- and remineralizing system for 2 weeks. The lesions were characterized again by PLM and MRG after treatment. A significant reduction in lesion progression was found by PLM and MRG after treatment with either non-fluoridated or fluoridated milk when compared to the control group. Using quantitative MRG, mineral change and distribution in the lesions were recorded. A possible protective effect of fluoridated milk on root surface caries was supported by a reduction in the progression of the lesions and an increase in the mineral within the lesion.



Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Arends J, Christoffersen J, Ruben J, Jongebloed WL: Remineralization of bovine dentine in vitro: The influence of the fluoride content in solution on mineral distribution. Caries Res 1989;23:309–314.
  2. Arends J, Ruben JL, Christoffersen J, Jongebloed WL, Zuidgeest TGM: Remineralization of human dentine in vitro. Caries Res 1990;24:432–435.
  3. Brustman B: Impact of exposure to fluoride-adequate water n root surface caries in the elderly. Gerodontol 1986;2:203–207.
  4. Burt BA, Ismail AI, Eklund SA: Root caries in an optimally fluoridated and a high fluoride community. J Dent Res 1986;65:1154–1158.
  5. Chow LC, Takagi S, Tung W, Jordan TH: Digital image analysis assisted microradiography: Measurement of mineral content of caries lesion in teeth. J Res NIST 1991;96:203–214.
  6. Clarkson BH, Hall DL, Heilman JR, Wefel JS: Effect of proteolytic enzymes on caries lesion formation in vitro. J Oral Pathol 1986;15:423–429.
  7. Cutress TW, Suckling GW, Coote GE, Gao J: Uptake of dietary fluoride from milk into the developing teeth of sheep (abstract). J Dent Res 1995;74:564.
  8. Ettinger RL, Bergman W, Wefel JS: Effect of fluoride on overdenture abutments. Am J Dent 1994;7:17–21.
  9. Heilman JR, Jordan TH, Warwick R, Wefel JS: Remineralization of root surfaces demineralized in solutions of differing fluoride levels. Caries Res 1997;31:423–428.
  10. Holt C, Dalgleish DG, Jennes R: Calculation on the ionic equilibria in milk diffusate and comparison with experiment. Anal Biochem 1981;113:154–163.
  11. Hoppenbrouwers PMM, Driessens FCM, Broggreven JMPM: The mineral solubility of human tooth roots. Arch Oral Biol 1987;32:319–322.
  12. Hunt RJ, Eldridge JB, Beck JD: Effect of residence in a fluoridated community on the incidence of coronal and root caries in an older adult population. J Publ Health Dent 1989;49:138–141.
  13. Jensen ME, Kohout F: The effect of a fluoridated dentifrice on root and coronal caries in an older adult population. J Am Dent Assoc 1988;117:829–832.
  14. Kawasaki K, Ruben J, Tsuda H, Huysmans MCDNJM, Takagi O: Relationship between mineral distribution in dentine lesions and subsequent remineralization in vitro. Caries Res 2000;34:395–403.
  15. McDougall WA: Effect of milk on enamel demineralization and remineralization in vitro. Caries Res 1977;11:166–172.
  16. Mukai Y, Lagerweij MD, ten Cate JM: Effect of a solution with high fluoride concentration on remineralization of shallow and deep root surface caries in vitro. Caries Res 2001;35:317–324.
  17. Phillips PC: Fluoride availability in fluoridated milk system. Caries Res 1991;29:237.
  18. Stephen KW, Banoczy J, Pakhomov GN: Milk Fluoridation for the Prevention of Dental Caries. Geneva, WHO/BDMF, 1996.
  19. ten Cate JM, Duijsters PPE: Alternating demineralization and remineralization of artificial enamel lesions. Caries Res 1982;16:201–210.
  20. Wallace MC, Retief DH, Bradley EL: The 48-month increment of root caries in an urban population of older adults participating in a preventive dental program. J Publ Health Dent 1993;53:133–137.
  21. Wefel JS, Clarkson BH, Heilman JR: Histology of root surface caries: in Thylstrup A, Leach SA, Quist A (eds): Dentine and Dentine Reactions in the Oral Cavity. Oxford, IRL Press, 1987, pp 117–125.
  22. Wefel JS, Heilman JR, Jordan TH: Comparison of in vitro root caries models. Caries Res 1995;29:204–209.


Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50