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Vol. 43, No. 3, 2000
Issue release date: May–June 2000 (October 2000)
Section title: Short Communication
Intervirology 2000;43:185–190

A Vestigial X Open Reading Frame in Duck Hepatitis B Virus

Lin B. · Anderson D.A.
Macfarlane Burnet Centre for Medical Research, Fairfield, Melbourne, Australia
email Corresponding Author

Dr. David Anderson

Head, Hepatitis Research Unit, Macfarlane Burnet Centre for Medical Research

Yarra Bend Road, Fairfield, Vic. 3078 (Australia)

Tel. +61 3 9282 2239, Fax +61 3 9282 2100


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Duck hepatitis B virus (DHBV) appears to lack a homologue of the X protein found in mammalian hepadnaviruses. By replacing stop codons in the corresponding region of the DHBV genome, a hypothetical protein which closely matches the hydrophilicity profile of X proteins can be predicted, despite limited sequence homology. We conclude that a full-length X protein was once a common feature of the hepadnaviruses, conserved in structure but not sequence.

© 2000 S. Karger AG, Basel

Article / Publication Details

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Abstract of Short Communication

Published online: 10/23/2000

Number of Print Pages: 6
Number of Figures: 5
Number of Tables: 0

ISSN: 0300-5526 (Print)
eISSN: 1423-0100 (Online)

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