Dementia in Clinical Practice

Editor(s): Giannakopoulos P. (Geneva) 
Hof P.R. (New York, N.Y.) 
Table of Contents
Vol. 24, No. , 2009
Section title: Vascular Dementia
Giannakopoulos P, Hof PR (eds): Dementia in Clinical Practice. Front Neurol Neurosci. Basel, Karger, 2009, vol 24, pp 79–85

The Concept of Vascular Cognitive Impairment

Erkinjuntti T.a · Gauthier S.b
aMemory Research Unit, Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland; bMcGill Center for Studies in Aging, McGill University, Montréal, Que., Canada
email Corresponding Author

Prof. Timo Erkinjuntti

Memory Research Unit, Department of Neurology

Helsinki University Central Hospital

PO Box 300, FI–00029 Helsinki (Finland)

Tel. +358 40 5000 827

Fax +358 94 7172 352


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Vascular cognitive impairment (VCI) is the modern term related to vascular burden of the brain,reflecting all encompassing effects of cerebrovascular disease (CVD) on cognition. VCI include alllevels of cognitive decline from mild deficits in one or more cognitive domains to a broad dementialikesyndrome. VCI incorporates the complex interactions between vascular risk factors, CVD etiologiesand cellular changes within the brain and cognition. Vascular risk factors towards VCI include,e.g. arterial hypertension, high cholesterol, and diabetes. VCI includes the common poststrokedementia and vascular dementia (VaD). The main subtypes of VaD include the cortical VaD or multiinfarctdementia also referred as poststroke VaD and subcortical ischemic vascular disease anddementia or small vessel dementia. Traditional vascular risk factors and stroke are also independentfactors for the clinical presentation of Alzheimer’s disease. In addition to these vascular factors, CVD/strokes, infarcts and white matter lesions may trigger and modify progression of Alzheimer’s disease.Whilst CVD is preventable and treatable, it clearly is a major factor in the prevalence of cognitiveimpairment in the elderly worldwide.

© 2009 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Vascular Dementia

Published online: 1/26/2009
Cover Date: 2009

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISBN: 978-3-8055-9015-0 (Print)
eISBN: 978-3-8055-9016-7 (Online)

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