Vascular cognitive impairment (VCI) is the modern term related to vascular burden of the brain,reflecting all encompassing effects of cerebrovascular disease (CVD) on cognition. VCI include alllevels of cognitive decline from mild deficits in one or more cognitive domains to a broad dementialikesyndrome. VCI incorporates the complex interactions between vascular risk factors, CVD etiologiesand cellular changes within the brain and cognition. Vascular risk factors towards VCI include,e.g. arterial hypertension, high cholesterol, and diabetes. VCI includes the common poststrokedementia and vascular dementia (VaD). The main subtypes of VaD include the cortical VaD or multiinfarctdementia also referred as poststroke VaD and subcortical ischemic vascular disease anddementia or small vessel dementia. Traditional vascular risk factors and stroke are also independentfactors for the clinical presentation of Alzheimer’s disease. In addition to these vascular factors, CVD/strokes, infarcts and white matter lesions may trigger and modify progression of Alzheimer’s disease.Whilst CVD is preventable and treatable, it clearly is a major factor in the prevalence of cognitiveimpairment in the elderly worldwide.
© 2009 S. Karger AG, Basel
Article / Publication Details
Published online: 1/26/2009
Cover Date: 2009
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISBN: 978-3-8055-9015-0 (Print)
eISBN: 978-3-8055-9016-7 (Online)
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