Journal Mobile Options
Table of Contents
Vol. 55, No. 5, 2011
Issue release date: September–October

Key Cytological Findings in FNA from Infantile Digital Fibromatosis

Ojha S.S. · Naik L.P. · Fernandes G.C. · Sathe P.A. · Kandalkar B.M.
To view the fulltext, log in and/or choose pay-per-view option

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Abstract

Background: Infantile digital fibromatosis (IDF) or inclusion body fibromatosis is a benign proliferation of fibroblastic and myofibroblastic cells. Its most common site is the digits of young children and it is named for the intracytoplasmic inclusions that are detected in lesional cells. Case: A two and a half-year-old male child presented with a single flesh-colored nodule on the dorsal aspect of his right little toe since the sixth month of life. FNAC from the lesion showed characteristic cytomorphological features of IDF. Conclusion: IDF is a rare lesion occurring in children or infants. There are many case reports describing histopathological features of IDF. To our knowledge, the typical inclusion bodies as cytomorphological findings in IDF have not been described in the literature. This is a rare case diagnosed on cytology and confirmed on histopathology.



Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Chirayil PT, Jayaraj J, Kumar P: Infantile digital fibromatosis – a case report. Burns 2001;27:89–90.
  2. Reye RD: Recurring digital fibrous tumors of childhood. Arch Pathol 1965;80:228–231.
  3. Coffin CM, Dehner LP: Fibroblastic-myofibroblastic tumors in children and adolescents: a clinicopathologic study of 108 examples in 103 patients. Pediatr Pathol 1991;11:569–588.
  4. Purdy LJ, Colby TV: Infantile digital fibromatosis occurring outside the digit. Am J Surg Pathol 1984;8:787–790.
  5. Niamba P, Leaute-Labreze C, Boralevi F, et al: Further documentation of spontaneous regression of infantile digital fibromatosis. Pediatr Dermatol 2007;24:280–284.
  6. Mukai M, Torikata C, Iri H, Hata J, Naito M, Shimoda T: Immunohistochemical identification of aggregated actin filaments in formalin fixed, paraffin- embedded sections. 1. A study of infantile digital fibromatosis by a new pretreatment. Am J Surg Pathol 1992;16:110–115.
  7. Grenier N, Liang C, Capaldi L, et al: A range of histologic findings in infantile digital fibromatosis. Pediatr Dermatol 2008;25:72–75.
  8. Choi KC, Hashimoto K, Setoyama M, Kagetsu N, Tronnier M, Sturman S: Infantile digital fibromatosis: immunohistochemical and immunoelectron microscopic studies. J Cutan Pathol 1990;17:225–232.
  9. Hayashi T, Tsuda N, Chowdhury PR, Anami M, Kishikawa M, Iseki M, Kobayashi K: Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. Mod Pathol 1995;8:548–552.
  10. Beckett JH, Jacobs AH: Recurring digital fibrous tumors of childhood: a review. Pediatrics 1977;59:401–406.
  11. Khan N, Alam K, Maheshwari V, et al: Recurrent infantile digital fibromatosis – a rare entity. Indian J Pathol Microbiol 2001;44:135–136.
  12. Ostrowski ML, Bradshaw J, Garrison D: Infantile myofibromatosis: diagnosis suggested by fine-needle aspiration biopsy. Diagn Cytopathol 1990;6:284–288.


Pay-per-View Options
Direct payment This item at the regular price: USD 33.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 23.00