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Background: Infantile digital fibromatosis (IDF) or inclusion body fibromatosis is a benign proliferation of fibroblastic and myofibroblastic cells. Its most common site is the digits of young children and it is named for the intracytoplasmic inclusions that are detected in lesional cells. Case: A two and a half-year-old male child presented with a single flesh-colored nodule on the dorsal aspect of his right little toe since the sixth month of life. FNAC from the lesion showed characteristic cytomorphological features of IDF. Conclusion: IDF is a rare lesion occurring in children or infants. There are many case reports describing histopathological features of IDF. To our knowledge, the typical inclusion bodies as cytomorphological findings in IDF have not been described in the literature. This is a rare case diagnosed on cytology and confirmed on histopathology.
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- Chirayil PT, Jayaraj J, Kumar P: Infantile digital fibromatosis – a case report. Burns 2001;27:89–90.
- Reye RD: Recurring digital fibrous tumors of childhood. Arch Pathol 1965;80:228–231.
- Coffin CM, Dehner LP: Fibroblastic-myofibroblastic tumors in children and adolescents: a clinicopathologic study of 108 examples in 103 patients. Pediatr Pathol 1991;11:569–588.
- Purdy LJ, Colby TV: Infantile digital fibromatosis occurring outside the digit. Am J Surg Pathol 1984;8:787–790.
- Niamba P, Leaute-Labreze C, Boralevi F, et al: Further documentation of spontaneous regression of infantile digital fibromatosis. Pediatr Dermatol 2007;24:280–284.
- Mukai M, Torikata C, Iri H, Hata J, Naito M, Shimoda T: Immunohistochemical identification of aggregated actin filaments in formalin fixed, paraffin- embedded sections. 1. A study of infantile digital fibromatosis by a new pretreatment. Am J Surg Pathol 1992;16:110–115.
- Grenier N, Liang C, Capaldi L, et al: A range of histologic findings in infantile digital fibromatosis. Pediatr Dermatol 2008;25:72–75.
- Choi KC, Hashimoto K, Setoyama M, Kagetsu N, Tronnier M, Sturman S: Infantile digital fibromatosis: immunohistochemical and immunoelectron microscopic studies. J Cutan Pathol 1990;17:225–232.
- Hayashi T, Tsuda N, Chowdhury PR, Anami M, Kishikawa M, Iseki M, Kobayashi K: Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. Mod Pathol 1995;8:548–552.
- Beckett JH, Jacobs AH: Recurring digital fibrous tumors of childhood: a review. Pediatrics 1977;59:401–406.
- Khan N, Alam K, Maheshwari V, et al: Recurrent infantile digital fibromatosis – a rare entity. Indian J Pathol Microbiol 2001;44:135–136.
- Ostrowski ML, Bradshaw J, Garrison D: Infantile myofibromatosis: diagnosis suggested by fine-needle aspiration biopsy. Diagn Cytopathol 1990;6:284–288.