Surgically Curable Non-Iron Deficiency Microcytic Anemia: Castleman’s DiseaseWeng C.-H.a · Chen J.-B.b · Wang J.c · Wu C.-C.d · Yu Y.c · Lin T.-H.a,e,f
a Division of Hematology/Oncology, Department of Internal Medicine, b Division of Colorectal Surgery, Department of Surgery, c Department of Pathology and Laboratory Medicine, d Division of General Surgery, Department of Surgery, Taichung Veterans General Hospital, e General Education Center, Central Taiwan University of Science and Technology, f Department of Internal Medicine, Chung-Shan Medical University Hospital, Taichung, Taiwan
Background: Castleman’s disease (CD) is a rare, benign lymphoproliferative disorder that can involve single lymph node stations or can be systemic. Unicentric CD in patients with microcytic anemia is rarely described in the English literature. Case Report: We describe the case of a 19-year-old Chinese woman with hyaline vascular type of unicentric CD presenting as severe non-iron deficiency microcytic anemia. We report the clinical course from the initial presentation to diagnosis and surgical cure, and discuss the most up-to-date information on CD. Conclusions: CD should be included in the differential diagnosis of microcytic anemia. Imaging tools and pathological studies should be considered in order to make a more accurate diagnosis and to avoid the use of ineffective treatments.