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Table of Contents
Vol. 56, No. 5, 2012
Issue release date: September–October
Section title: Fine Needle Aspiration
Acta Cytologica 2012;56:501–505
(DOI:10.1159/000341626)

Fine-Needle Aspiration Cytology of Mammary Myofibroblastoma: A Report of Six Cases

Álvarez-Rodriguez F. · Gimeno-Aranguez M. · López-Varela C. · González-Peramato P. · Tortoledo-Bruni A. · Rodríguez-Costa J. · Perna C. · Jiménez-Heffernan J.A.
Departments of Pathology,aHospital La Zarzuela, bUniversity Hospital Infanta Leonor, cUniversity Hospital Gregorio Marañón, dUniversity Hospital La Paz, and eUniversity Hospital Puerta de Hierro, Madrid, and fUniversity Hospital Guadalajara, Guadalajara, Spain

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Article / Publication Details

First-Page Preview
Abstract of Fine Needle Aspiration

Received: 5/29/2012 1:40:16 PM
Accepted: 7/5/2012
Published online: 9/27/2012

Number of Print Pages: 5
Number of Figures: 1
Number of Tables: 1

ISSN: 0001-5547 (Print)
eISSN: 1938-2650 (Online)

For additional information: http://www.karger.com/ACY

Abstract

Objective: To evaluate cytologic features of mammary myofibroblastoma in order to establish the possibility of precise preoperative recognition. Study Design: This was a multi-institutional study of 6 patients with myofibroblastoma (5 men and 1 woman) in which preoperatively fine-needle aspiration cytology was performed. Four cases showed classical histologic features, 1 corresponded to the cellular variant and the remaining 1 to the fibrous form. Results: Except for 1 case, smears were cellular and distributed as irregular aggregates and single cells. Most groups showed a small amount of metachromatic stroma and capillaries. Cells retained cytoplasm and showed a spindle-to-plump oval morphology with moderate pleomorphism. Nuclear pleomorphism was present and was relevant in 1 case. Intranuclear pseudoinclusions and mast cells were present in 3 cases. No epithelial clusters were seen. Due to hypercellularity and pleomorphism 1 case was considered as suspicious for malignancy. The remaining 5 were diagnosed as low-grade mesenchymal lesions, and myofibroblastoma was suggested in 3. Conclusion: Cytologic features of myofibroblastoma reflect what is seen on histology. When such findings are correlated with image studies, preoperative recognition can be possible. This is especially true for male patients in whom the tumor is relatively frequent.


Article / Publication Details

First-Page Preview
Abstract of Fine Needle Aspiration

Received: 5/29/2012 1:40:16 PM
Accepted: 7/5/2012
Published online: 9/27/2012

Number of Print Pages: 5
Number of Figures: 1
Number of Tables: 1

ISSN: 0001-5547 (Print)
eISSN: 1938-2650 (Online)

For additional information: http://www.karger.com/ACY


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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