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Status: available   
Publication year: 2010

New Drugs and Targets for Asthma and COPD

Editor(s): Hansel T.T. (London) 
Barnes P.J. (London) 


This book belongs to
Progress in Respiratory Research , Vol. 39
Editor(s): Herth F.J.F. (Heidelberg) 
XIV + 310 p., 80 fig., 67 in color, 46 tab., hard cover, 2010
Status: available   
ISSN: 1422-2140
e-ISSN: 1662-3932

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Foreword and Preface (Free PDF)

Free Sample Chapters

 ·  J.A. Mitchell, R. Sorrentino, N. Cartwright, M. Paul-Clark:
    Toll-like receptor 2 as therapeutic target in lung disease
    Free Access

 ·  R. Marshall, I. Faiferman:
    IL-5-directed approaches in the treatment of eosinophil-driven disease
    Free Access


Reporting the latest progress
Asthma, allergy and chronic obstructive lung disease are common throughout the world and are increasing in incidence, particularly in the developing world.
This volume provides a state-of-the-art account of the identification of new targets and the development of new therapies for these conditions. Some 40 chapters by clinical academics and senior members of the pharmaceutical industry detail the latest breakthroughs in research and development. In asthma, a promising approach is the use of therapy directed against specific Th2 responses through biological antagonists of IL-5, IL-4 and IL-13. There have also been major advances in our understanding of innate immune responses to pathogen-associated molecular patterns, and in the area of Toll-like receptors.

Up to date and comprehensive, this book will be of particular relevance to those working in the pharmaceutical industry (in preclinical research and clinical development), to academic researchers in the field of respiratory medicine, and to respiratory health care specialists.

Bibliographic Details

Progress in Respiratory Research, Vol. 39
New Drugs and Targets for Asthma and COPD
Editor(s): Hansel T.T. (London) 
Barnes P.J. (London) 
XIV + 310 p., 80 fig., 67 in color, 46 tab., hard cover, 2010
Status: available   
ISBN: 978-3-8055-9566-7
e-ISBN: 978-3-8055-9567-4
DOI: 10.1159/isbn.978-3-8055-9567-4