Advanced Therapies in Pediatric Endocrinology and Diabetology
Dealing with current hot topics, this book aims to provide an update on advances in the treatment of endocrine disorders. The chapters cover innovative therapeutic approaches to type 1 diabetes, such as artificial pancreas and islet transplantation. Additionally, novel pharmacological interventions for patients with obesity and the metabolic syndrome, as well as with adrenal and gonadal disorders are provided. Furthermore, recent developments in growth-promoting therapies, such as the C-type natriuretic peptide analog to treat achondroplasia, as well as antioxidant and gene replacement therapies in patients with adrenoleukodystrophy, are described. Worldwide renowned experts share their experience and cutting edge research in Advanced Therapies in Pediatric Endocrinology and Diabetology, which makes it a useful and interesting resource for every pediatric endocrinologist, not only those active in clinical research, but also those involved in the management of children with endocrine diseases in daily practice.
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Table of Contents
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1 - 13: Toward Automation of Insulin Delivery - Management Solutions for Type 1 DiabetesByRevital Nimri;Revital NimriaThe Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, andSearch for other works by this author on:Moshe PhillipMoshe PhillipaThe Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, andbSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelSearch for other works by this author on:
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14 - 22: Islet Transplantation in Pediatric Patients: Current Indications and Future PerspectivesByBarbara Antonioli;Barbara AntoniolibTissue Therapy Unit andSearch for other works by this author on:Giacomo ColussiGiacomo ColussicNephrology Department, Niguarda Hospital, Milan, ItalySearch for other works by this author on:
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23 - 28: Glucagon-Like Peptide-1 Receptor Agonist Treatment for Pediatric ObesityByAaron S. KellyAaron S. KellyDepartments of Pediatrics and Medicine, University of Minnesota Medical School, and University of Minnesota Masonic Children's Hospital, Minneapolis, Minn., USASearch for other works by this author on:
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29 - 36: Docosahexaenoic Acid and Its Role in G-Protein-Coupled Receptor 120 Activation in Children Affected by Nonalcoholic Fatty Liver DiseaseByClaudia Della Corte;Claudia Della CorteaHepato-Metabolic Disease Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, andSearch for other works by this author on:Antonella Mosca;Antonella MoscaaHepato-Metabolic Disease Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, andSearch for other works by this author on:Aurelio Ionata;Aurelio IonatabAzienda Sanitaria Regionale del Molise (A.S.Re.M), Isernia, ItalySearch for other works by this author on:Valerio NobiliValerio NobiliaHepato-Metabolic Disease Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, andSearch for other works by this author on:
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37 - 41: Noninvasive Prenatal Diagnosis of Congenital Adrenal HyperplasiaByAhmed Khattab;Ahmed KhattabaDepartments of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA;Search for other works by this author on:Tony Yuen;Tony YuenaDepartments of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA;Search for other works by this author on:Li Sun;Li SunaDepartments of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA;Search for other works by this author on:Mabel Yau;Mabel YauaDepartments of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA;Search for other works by this author on:Ariella Barhan;Ariella BarhanaDepartments of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA;Search for other works by this author on:Mone Zaidi;Mone ZaidiaDepartments of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA;Search for other works by this author on:Y.M. Dennis Lo;Y.M. Dennis LobDepartment of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, SAR, ChinaSearch for other works by this author on:Maria I. NewMaria I. NewaDepartments of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA;Search for other works by this author on:
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42 - 53: Recent Advances in Hydrocortisone Replacement TreatmentByAshwini Mallappa;Ashwini MallappaaClinical Center, National Institutes of Health, Bethesda, Md., USA;Search for other works by this author on:Miguel DebonoMiguel DebonobAcademic Unit of Endocrinology, The Medical School, University of Sheffield, Sheffield, UKSearch for other works by this author on:
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54 - 59: Experience with the Histrelin Implant in Pediatric PatientsByErica A. EugsterErica A. EugsterDepartment of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Ind., USASearch for other works by this author on:
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60 - 78: Different Medications for Hypogonadotropic HypogonadismByGiulia Rastrelli;Giulia RastrelliSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences Mario Serio, University of Florence, Florence, ItalySearch for other works by this author on:Linda Vignozzi;Linda VignozziSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences Mario Serio, University of Florence, Florence, ItalySearch for other works by this author on:Mario MaggiMario MaggiSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences Mario Serio, University of Florence, Florence, ItalySearch for other works by this author on:
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79 - 97: Long-Acting Growth Hormone: An UpdateByPaul H. Saenger;Paul H. SaengerDivision of Pediatric Endocrinology, Department of Pediatrics, Winthrop University Hospital, Mineola, New York, N.Y., USASearch for other works by this author on:Jorge Mejia-CorlettoJorge Mejia-CorlettoDivision of Pediatric Endocrinology, Department of Pediatrics, Winthrop University Hospital, Mineola, New York, N.Y., USASearch for other works by this author on:
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98 - 105: C-Type Natriuretic Peptide Analog as Therapy for AchondroplasiaByLaurence Legeai-MalletLaurence Legeai-MalletINSERM U1163, Institut Imagine, Université Paris Descartes-Sorbonne Paris Cité, Paris, FranceSearch for other works by this author on:
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106 - 129: Therapeutic Neuroendocrine Agonist and Antagonist Analogs of Hypothalamic Neuropeptides as Modulators of the Hypothalamic-Pituitary-Gonadal AxisByClaire L. Newton;Claire L. NewtonaCentre for Neuroendocrinology, Department of Immunology, Faculty of Health Sciences, andcUCT/MRC Receptor Biology Unit, Medical Biochemistry and Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South AfricaSearch for other works by this author on:Ross C. Anderson;Ross C. AndersonaCentre for Neuroendocrinology, Department of Immunology, Faculty of Health Sciences, andcUCT/MRC Receptor Biology Unit, Medical Biochemistry and Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South AfricaSearch for other works by this author on:Robert P. MillarRobert P. MillaraCentre for Neuroendocrinology, Department of Immunology, Faculty of Health Sciences, andbThe Mammal Research Institute, Department of Zoology and Entomology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, andcUCT/MRC Receptor Biology Unit, Medical Biochemistry and Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South AfricaSearch for other works by this author on:
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130 - 140: Aromatase Inhibitors in the Treatment of Short StatureByMatti HeroMatti HeroChildren's Hospital, Helsinki University Central Hospital (HUCH), Helsinki, FinlandSearch for other works by this author on:
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141 - 146: Gene Therapy for Rare Central Nervous System Diseases Comes to AgeByPatrick AubourgPatrick AubourgINSERM U1169, Department of Pediatric Neurology, Bicêtre Hospital, and Paris-Sud University, Le Kremlin-Bicêtre, FranceSearch for other works by this author on:
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147 - 160: Novel Therapeutic Targets and Drug Candidates for Modifying Disease Progression in AdrenoleukodystrophyByAurora PujolAurora PujolLaboratory of Neurometabolic Diseases and Pathologic Anatomy Service, Institute of Neuropathology, Bellvitge Biomedical Research Institute (IDIBELL)-Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat and Center for Biomedical Research on Rare Diseases (CIBERER), U759, ISCIII, and Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, SpainSearch for other works by this author on: