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Spotlight


Schwerpunkt: Pulmonal-arterielle Hypertonie
 

Schwerpunkt: Pulmonal-arterielle Hypertonie

Kein anderes pneumologisches Feld hat sich in den letzten Jahrzenten derart gewandelt wie die Forschung zur pulmonalen Hypertonie Aus einer unbehandelbaren, rasch tödlich verlaufenden Erkrankung ist eine gut charakterisierte Erkrankung mit multiplen Therapieoptionen geworden. Jedoch warten Patienten in Deutschland derzeit noch einige Jahre ab Feststellung der ersten Symptome der pulmonalen Hypertonie (Belastungsdyspnoe, Leistungsminderung, Synkopen), bis eine Diagnosestellung innerhalb der klinischen Klassifikation erfolgt. Dieses Heft bildet einen spannenden Ein- und Überblick zum aktuellen Stand der Forschung.

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 Special Topic: Immunotherapies in Solid Tumors
 

Special Topic: Immunotherapies in Solid Tumors

For a long time, progress in cancer therapy only occurred in small steps. However, with the increasing knowledge of the mechanisms and molecules involved in tumor development, this has changed considerably over the past 20 years. The early 90’s saw the successful development of targeted therapies. Targets involved in the progression of tumors were identified and validated, and drugs that were shown to interfere with the activity of such targets were developed and confirmed to be clinically effective. Recently, a paradigmatic change in cancer therapy occurred with the development of checkpoint inhibitors. These advances in cancer immunotherapy are very promising not only because they provide more efficient treatment for some patients, but even more because they provide a concept for a paradigmatic change in cancer therapy. This special issue summarize our current knowledge about the clinical benefit of immunotherapies in brain, breast, colorectal, lung, kidney, and skin cancer.

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 Joint Congress of the of EASO and IFSO-EC
 

Joint Congress of the of EASO and IFSO-EC

Supplemental Issue containing the Abstracts of the Joint Congress of the of EASO and IFSO-EC, Gothenburg, June 1–4, 2016 – European Obesity Summit (EOS)

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 Special Topic: New Diagnostic Strategies in Infection Safety
 

Special Topic: New Diagnostic Strategies in Infection Safety

Infection safety of blood components is still a major topic in transfusion medicine. In the last decades the worldwide routine implementation of nucleic acid amplification techniques (NAT) has led to the prevention of several transfusion-transmitted infections. The main emphasis was placed on the Big Three: hepatitis C virus (HCV), human immunodeficiency virus (HIV), and hepatitis B virus (HBV). In addition, further targets were tested (e.g. hepatitis A virus (HAV), parvovirus B19 (B19V)) due to the requirements of the plasma fractionation industry or, in the case of West-Nile virus (WNV) or hepatitis E virus (HEV), due to new risk assessments. Altogether, this issue of TRANSFUSION MEDICINE AND HEMOTHERAPY provides an insight into new developments in NAT screening of blood donations, focusing on novel targets and full automation of testing, leading to the further improvement of blood safety.

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 30. Schweizerischen Jahrestagung für Phytotherapie
 

30. Schweizerischen Jahrestagung für Phytotherapie

Dieses Heft enthält die Beiträge der 30. Schweizerischen Jahrestagung für Phytotherapie, die am 12. November 2015 in Baden/Schweiz zum Thema „Phytotherapie in der Pädiatrie und für stillende Mütter – zwischen Evidenz und praktischer Erfahrung“ stattfand.

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