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Special Article

The Treatment of Psychotic Major Depression: Is There a Role for Adjunctive Psychotherapy?

Gaudiano B.A.a · Miller I.W.a · Herbert J.D.b

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aDepartment of Psychiatry and Human Behavior, Brown Medical School and Butler Hospital, Providence, R.I., and bDepartment of Psychology, Drexel University, Philadelphia, Pa., USA

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Psychother Psychosom 2007;76:271–277

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Article / Publication Details

First-Page Preview
Abstract of Special Article

Published online: August 16, 2007
Issue release date: August 2007

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 1

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: https://www.karger.com/PPS

Abstract

Background: Psychotic depression is a relatively prevalent mood disorder associated with greater symptom severity, a poorer course of illness and higher levels of functional impairment compared with nonpsychotic depression. Separate lines of investigation suggest that various forms of cognitive-behavioral therapy are efficacious for treating severe forms of nonpsychotic depression as well as primary psychotic disorders. However, there currently are no empirically supported psychotherapies specifically designed for treating psychotic depression. Method: We review the efficacy of current somatic treatments for the disorder and discuss the limited data to date on potentially useful psychotherapeutic approaches. In particular, we describe the clinical improvement observed in a subgroup of hospitalized patients with psychotic depression treated with Acceptance and Commitment Therapy as part of a larger clinical trial. Results: Pilot results demonstrated that Acceptance and Commitment Therapy was associated with clinically significant reductions in acute symptom severity and impairment compared with treatment as usual. Conclusion: The findings suggest that patients with psychotic depression can benefit from psychotherapy. Clinical and research recommendations in this area are presented.

© 2007 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Special Article

Published online: August 16, 2007
Issue release date: August 2007

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 1

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: https://www.karger.com/PPS


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