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Original Paper

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Pulmonary Ventilatory Functions and Obesity in Kuwait

Al-Bader W.R.a · Ramadan J.b · Nasr-Eldin A.a, b · Barac-Nieto M.b

Author affiliations

aMinistry of Public Health, Hawali Health Area, Rumaythia Polyclinic, and bDepartment of Physiology, Faculty of Medicine, Kuwait University, Kuwait

Corresponding Author

Dr. Jasem Ramadan

Department of Physiology, Faculty of Medicine

PO Box 24923, Safat 13110 (Kuwait)

Tel. +965 531 9594, Fax +965 533 8937

E-Mail Ramadan@hsc.edu.kw

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Med Princ Pract 2008;17:20–26

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Objective: To study the relationship between obesity and pulmonary ventilatory functions in Kuwaiti adults. Subjects and Methods: A total of 200 male and 180 female Kuwaiti adults aged 20–65 years were investigated in six medical centers from April 2004 to March 2006. Parameters measured included forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1 as a percentage of FVC (FEV%); body mass index (BMI in kg/m2) and waist-to-hip ratio (W/H). Results: For the whole group, males or females, BMI (kg·m2) and W/H were poor individual predictors of pulmonary ventilatory functions. However, central adiposity (W/H) was associated with restrictive respiratory impairment (10.6–13.9% decrease in FEV1 and 10–12.3% decrease in FVC), independent of sex, age or height. In obese females and males (BMI >30), increasing severity of obesity was significantly associated (p < 0.05, R2 >0.06) associated with increasing restrictive respiratory impairment (8.7–14.4% decrease in FEV1 and 8–11.7% decrease in FVC), with no evidence of obstructive disease (FEV1/FVC >0.8). Conclusion: In adult Kuwaiti males and females, increase in body fat at BMI >30 or W/H >1 was associated with a restrictive effect on pulmonary ventilation.

© 2007 S. Karger AG, Basel


  1. World Health Organization: Controlling the global obesity epidemic. Geneva, WHO, 2003. http/http//www.who.int/nutrition/topics/obesity/en/index.html. Accessed January 31, 2006.
  2. American Thoracic Society Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 1991;144:1202–1218.
  3. Quanjer PH, Tammeeling GJ, Cotes JA, Pedresen OF, Peslin R, Yernault JC: Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Testing. European Community for Steel and Coal. Official Statement of European Respiratory Society. Eur Respir J 1993;6:5–40.
  4. Hutchinson J: On the capacity of the lungs, and on the respiratory functions, with a view of establishing a precise and easy method for detecting disease by spirometer. Med Chir Trans 1846;29:137–252.
  5. Baltopoulos G, Fildisis G, Karatazas S, Georgiakodis F, Myrianthefs P: Reference values and prediction equations for FVC and FEV1 in Greek elderly. Lung 2000;178:201–212.
  6. Paoletti P, Pistelli G, Fazzi P, Viegi G, Di Pede F, Giuliano G, Prediletto R, Carrozzi L, Polato R, Saetta M: Reference values for vital capacity and flow-volume curves from a general population study. Bull Eur Physiopathol Respir 1986;22:451–459.
  7. Lazarus R, Gore C J, Booth M, Owen N: Effects of body composition and fat distribution on ventilatory function in adults. Am J Clin Nutr 1998;68:35–41.
  8. Santana H, Zoico E, Tosoni P, Bissoli L, Olivieri M, Bosello O, Zamboni M: Relation between body composition, fat distribution, and lung function in elderly men. Am Clin Nutr 2001;73:827–831.
  9. Dockery DW, Ware JH, Ferris BG, Glicksberg DS, Fay ME, Spiro A, Speizer FE: Distribution of forced expiratory volume in one second and forced vital capacity in healthy, white adult, never-smokers in six US cities. Am Rev Respir Dis 1985;131:511–520.
  10. Luce JM: Respiratory complications of obesity. Chest 1980;78:626–631.
  11. Ray CS, Sue DY, Bary G, Hansen JE, Wasserman K: Effects of obesity on respiratory function. Am Rev Respir Dis 1983;128:501–506.
  12. Harik-Khan RI, Wise RA, Fleg JL: The effect of gender on the relationship between body fat distribution and lung function. J Clin Epidemiol 2001;54:399–406.
  13. Williamson DF: Measurement of waist-hip ratio, classification of obesity. Am J Hum Biol 1993;15:59–67.
  14. Cotes JE, Chinn DJ, Reed JW: Body mass, fat percentage, and fat-free mass as reference variables for lung function: effect on terms for age and sex. Thorax 2001;56:839–844.
  15. Schoenberg J, Beck G, Bouhuys A: Grow and decay of pulmonary function in healthy black and white. Respir Physiol 1978;33:367–393.
  16. Collins L, Hoberty P, Walker J, Flecher E, Peiris A: The effect of body fat distribution on pulmonary function tests. Chest 1995;107:1298–1302.
  17. Lazarus R, Sparrow D, Weiss ST: Effects of obesity and fat distribution on ventilatory function. Chest 1997;111:891–898.
  18. Al-Issa AN: Prevalence of obesity among adult Kuwaitis: across-sectional study. Int J Obes Relat Metab Disord 1995;19:431–433.

Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: December 05, 2006
Published online: April 22, 2008
Issue release date: December 2007

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 3

ISSN: 1011-7571 (Print)
eISSN: 1423-0151 (Online)

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