Login to MyKarger

New to MyKarger? Click here to sign up.



Login with Facebook

Forgot your password?

Authors, Editors, Reviewers

For Manuscript Submission, Check or Review Login please go to Submission Websites List.

Submission Websites List

Institutional Login
(Shibboleth or Open Athens)

For the academic login, please select your country in the dropdown list. You will be redirected to verify your credentials.

ENETS Guidelines

Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Tumours: Well-Differentiated Tumour/Carcinoma of the Appendix and Goblet Cell Carcinoma

Plöckinger U.a · Couvelard A.b · Falconi M.c · Sundin A.d · Salazar R.e · Christ E.f · de Herder W.W.g · Gross D.h · Knapp W.H.i · Knigge U.P.j · Kulke M.H.k · Pape U.F.l

Author affiliations

aCharité Universitätsmedizin, Campus Virchow-Klinikum, Department of Hepatology and Gastroenterology, Berlin, Germany; bHôpital Beaujon, Service de Gastroenterologie, Clichy, France; cUniversity of Verona, Medicine and Surgery, General Surgery Section, MED/18 – General Surgery, Verona, Italy; dUppsala University Hospital, Department of Radiology, Uppsala, Sweden; eInstitut Català d’Oncologia, Barcelona, Spain; fEndokrinologie für Erwachsene, Inselspital, Bern, Switzerland; gDepartment of Internal Medicine, Section of Endocrinology, Erasmus MC, Rotterdam, The Netherlands; hDepartment of Endocrinology & Metabolism, Hadassah University Hospital, Jerusalem, Israel; iMHH, Klinik für Nuklearmedizin, Hannover, Germany; jDepartment of Surgery, C2122, Rigshospitalet Blegdamsvej, Copenhagen, Denmark; kDana-Farber Cancer Institute, Boston, Mass., USA;

Related Articles for ""

Neuroendocrinology 2008;87:20–30

Do you have an account?

Login Information





Contact Information











I have read the Karger Terms and Conditions and agree.



Login Information





Contact Information











I have read the Karger Terms and Conditions and agree.



To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

CHF 38.00 *
EUR 35.00 *
USD 39.00 *

Select

KAB

Buy a Karger Article Bundle (KAB) and profit from a discount!

If you would like to redeem your KAB credit, please log in.


Save over 20% compared to the individual article price.
Learn more

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00


Select

Subscribe

  • Access to all articles of the subscribed year(s) guaranteed for 5 years
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select

* The final prices may differ from the prices shown due to specifics of VAT rules.

Article / Publication Details

Published online: October 11, 2007
Issue release date: November 2007

Number of Print Pages: 11
Number of Figures: 1
Number of Tables: 3

ISSN: 0028-3835 (Print)
eISSN: 1423-0194 (Online)

For additional information: https://www.karger.com/NEN


First-Page Preview
Abstract of ENETS Guidelines

References

  1. Solcia E, Klöppel G, Sobin LH: Histological Typing of Endocrine Tumours, ed 2. WHO International Histological Classification of Tumours. Berlin, Springer, 2000.
  2. Caplin ME, Buscombe JR, Hilson AJ, Jones AL, Watkinson AF, Burroughs AK: Carcinoid tumour. Lancet 1998;352:799–805.
  3. Godwin JD 2nd: Carcinoid tumors. An analysis of 2,837 cases. Cancer 1975;36:560–569.
  4. Hemminki K, Li X: Incidence trends and risk factors of carcinoid tumors: a nationwide epidemiologic study from Sweden. Cancer 2001;92:2204–2210.
  5. Kulke MH, Mayer RJ: Carcinoid tumors. N Engl J Med 1999;340:858–868.
  6. Maggard MA, O’Connell JB, Ko CY: Updated population-based review of carcinoid tumors. Ann Surg 2004;240:117–122.
  7. Modlin IM, Lye KD, Kidd M: A five-decade analysis of 13,715 carcinoid tumors. Cancer 2003;97:934–959.
  8. Vinik AI, McLeod MK, Fig LM, Shapiro B, Lloyd RV, Cho K: Clinical features, diagnosis, and localization of carcinoid tumors and their management. Gastroenterol Clin North Am 1989;18:865–896.
  9. McGory ML, Maggard MA, Kang H, O’Connell JB, Ko CY: Malignancies of the appendix: beyond case series reports. Dis Colon Rectum 2005;48:2264–2271.
  10. Moertel CG, Dockerty MB, Judd ES: Carcinoid tumors of the vermiform appendix. Cancer 1968;21:270–278.
  11. O’Donnell ME, Carson J, Garstin WI: Surgical treatment of malignant carcinoid tumours of the appendix. Int J Clin Pract 2007;61:431–437.
  12. Sandor A, Modlin IM: A retrospective analysis of 1,570 appendiceal carcinoids. Am J Gastroenterol 1998;93:422–428.
  13. Goede AC, Caplin ME, Winslet MC: Carcinoid tumour of the appendix. Br J Surg 2003;90:1317–1322.
  14. Iwuagwu OC, Jameel JK, Drew PJ, Hartley JE, Monson JR: Primary carcinoma of the appendix – Hull series. Dig Surg 2005;22:163–167.
  15. Moertel CG, Weiland LH, Nagorney DM, Dockerty MB: Carcinoid tumor of the appendix: treatment and prognosis. N Engl J Med 1987;317:1699–1701.
  16. Stinner B, Rothmund M: Neuroendocrine tumours (carcinoids) of the appendix. Best Pract Res Clin Gastroenterol 2005;19:729–738.
  17. Deans GT, Spence RA: Neoplastic lesions of the appendix. Br J Surg 1995;82:299–306.
  18. McCusker ME, Cote TR, Clegg LX, Sobin LH: Primary malignant neoplasms of the appendix: a population-based study from the surveillance, epidemiology and end-results program, 1973–1998. Cancer 2002;94:3307–3312.
  19. Moertel CL, Weiland LH, Telander RL: Carcinoid tumor of the appendix in the first two decades of life. J Pediatr Surg 1990;25:1073–1075.
  20. Thirlby RC, Kasper CS, Jones RC: Metastatic carcinoid tumor of the appendix. Report of a case and review of the literature. Dis Colon Rectum 1984;27:42–46.
  21. Safioleas MC, Moulakakis KG, Kontzoglou K, Stamoulis J, Nikou GC, Toubanakis C, Lygidakis NJ: Carcinoid tumors of the appendix. Prognostic factors and evaluation of indications for right hemicolectomy. Hepatogastroenterology 2005;52:123–127.
  22. Syracuse DC, Perzin KH, Price JB, Wiedel PD, Mesa-Tejada R: Carcinoid tumors of the appendix. Mesoappendiceal extension and nodal metastases. Ann Surg 1979;190:58–63.
  23. Dunn JP: Carcinoid tumours of the appendix: 21 cases, with a review of the literature. NZ Med J 1982;95:73–76.
  24. Prommegger R, Obrist P, Ensinger C, Schwelberger HG, Wolf C, Fischer-Colbrie R, Mikuz G, Bodner E: Secretoneurin in carcinoids of the appendix-immunohistochemical comparison with chromogranins A, B and secretogranin II. Anticancer Res 1998;18:3999–4002.
  25. Rossi G, Valli R, Bertolini F, Sighinolfi P, Losi L, Cavazza A, Rivasi F, Luppi G: Does mesoappendix infiltration predict a worse prognosis in incidental neuroendocrine tumors of the appendix? A clinicopathologic and immunohistochemical study of 15 cases. Am J Clin Pathol 2003;120:706–711.
  26. MacGillivray DC, Heaton RB, Rushin JM, Cruess DF: Distant metastasis from a carcinoid tumor of the appendix less than one centimeter in size. Surgery 1992;111:466–471.
  27. Thompson GB, van Heerden JA, Martin JK Jr, Schutt AJ, Ilstrup DM, Carney JA: Carcinoid tumors of the gastrointestinal tract: presentation, management, and prognosis. Surgery 1985;98:1054–1063.
  28. Pickhardt PJ, Levy AD, Rohrmann CA Jr, Kende AI: Primary neoplasms of the appendix: radiologic spectrum of disease with pathologic correlation. Radiographics 2003;23:645–662.
  29. Dall’Igna P, Ferrari A, Luzzatto C, Bisogno G, Casanova M, Alaggio R, Terenziani M, Cecchetto G: Carcinoid tumor of the appendix in childhood: the experience of two Italian institutions. J Pediatr Gastroenterol Nutr 2005;40:216–219.
  30. Bamboat ZM, Berger DL: Is right hemicolectomy for 2.0-cm appendiceal carcinoids justified? Arch Surg 2006;141:349–352.
  31. Kanthan R, Saxena A, Kanthan SC: Goblet cell carcinoids of the appendix: immunophenotype and ultrastructural study. Arch Pathol Lab Med 2001;125:386–390.
  32. Pahlavan PS, Kanthan R: Goblet cell carcinoid of the appendix. World J Surg Oncol 2005;3:36.
  33. Bucher P, Gervaz P, Ris F, Oulhaci W, Egger JF, Morel P: Surgical treatment of appendiceal adenocarcinoid (goblet cell carcinoid). World J Surg 2005;29:1436–1439.
  34. Butler JA, Houshiar A, Lin F, Wilson SE: Goblet cell carcinoid of the appendix. Am J Surg 1994;168:685–687.
  35. Bader TR, Semelka RC, Chiu VC, Armao DM, Woosley JT: MRI of carcinoid tumors: spectrum of appearances in the gastrointestinal tract and liver. J Magn Reson Imaging 2001;14:261–269.
  36. Chiti A, Fanti S, Savelli G, Romeo A, Bellanova B, Rodari M, van Graafeiland BJ, Monetti N, Bombardieri E: Comparison of somatostatin receptor imaging, computed tomography and ultrasound in the clinical management of neuroendocrine gastroenteropancreatic tumours. Eur J Nucl Med 1998;25:1396–1403.
  37. Dromain C, de Baere T, Lumbroso J, Caillet H, Laplanche A, Boige V, Ducreux M, Duvillard P, Elias D, Schlumberger M, Sigal R, Baudin E: Detection of liver metastases from endocrine tumors: a prospective comparison of somatostatin receptor scintigraphy, computed tomography, and magnetic resonance imaging. J Clin Oncol 2005;23:70–78.
  38. Gabriel M, Decristoforo C, Kendler D, Dobrozemsky G, Heute D, Uprimny C, Kovacs P, Von Guggenberg E, Bale R, Virgolini IJ: 68GA-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and ct. J Nucl Med 2007;48:508–518.
  39. Bucher P, Gervaz P, Ris F, Oulhaci W, Inan I, Morel P: Laparoscopic versus open resection for appendix carcinoid. Surg Endosc 2006;20:967–970.
  40. Kawahara M, Kammori M, Kanauchi H, Noguchi C, Kuramoto S, Kaminishi M, Endo H, Takubo K: Immunohistochemical prognostic indicators of gastrointestinal carcinoid tumours. Eur J Surg Oncol 2002;28:140–146.
  41. Sokmensuer C, Gedikoglu G, Uzunalimoglu B: Importance of proliferation markers in gastrointestinal carcinoid tumors: a clinicopathologic study. Hepatogastroenterology 2001;48:720–723.
  42. Van Eeden S, Quaedvlieg PF, Taal BG, Offerhaus GJ, Lamers CB, Van Velthuysen ML: Classification of low-grade neuroendocrine tumors of midgut and unknown origin. Hum Pathol 2002;33:1126–1132.
  43. Rindi G, Kloppel G, Alhman H, Caplin M, Couvelard A, de Herder WW, Erikssson B, Falchetti A, Falconi M, Komminoth P, Korner M, Lopes JM, McNicol AM, Nilsson O, Perren A, Scarpa A, Scoazec JY, Wiedenmann B: TNM staging of foregut (neuro)- endocrine tumors: a consensus proposal including a grading system. Virchows Arch 2006;449:395–401.
  44. Mahteme H, Sugarbaker PH: Treatment of peritoneal carcinomatosis from adenocarcinoid of appendiceal origin. Br J Surg 2004;91:1168–1173.
  45. Pham TH, Wolff B, Abraham SC, Drelichman E: Surgical and chemotherapy treatment outcomes of goblet cell carcinoid: a tertiary cancer center experience. Ann Surg Oncol 2006;13:370–376.
  46. Garin L, Corbinais S, Boucher E, Blanchot J, Le Guilcher P, Raoul JL: Adenocarcinoid of the appendix vermiformis: complete and persistent remission after chemotherapy (Folfox) of a metastatic case. Dig Dis Sci 2002;47:2760–2762.
  47. Rindi G, Kloppel G, Convelard A, Komminoth P, Korner M, Lopes JM, McNicol AM, Nilsson O, Perren A, Scarpa A, Scoazec JY, Widenmann B: TNM staging of midgut and hindgut (neuro)endocrine tumors: a consensus proposal including a grading system. Virchows Arch 2007;451:757–762.

Article / Publication Details

Published online: October 11, 2007
Issue release date: November 2007

Number of Print Pages: 11
Number of Figures: 1
Number of Tables: 3

ISSN: 0028-3835 (Print)
eISSN: 1423-0194 (Online)

For additional information: https://www.karger.com/NEN


Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.