The Natural Incubation Period of Kuru and the Episodes of Transmission in Three Clusters of PatientsKlitzman R.L. · Alpers M.P. · Gajdusek D.C.
Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea; National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, Md., USA
Do you have an account?
- Rent for 48h to view
- Buy Cloud Access for unlimited viewing via different devices
- Synchronizing in the ReadCube Cloud
- Printing and saving restrictions apply
Rental: USD 8.50
Cloud: USD 20.00
Epidemiological data were collected on the slow virus disease, kuru, among the Fore cultural and linguistic group in Papua New Guinea from 65 kuru patients who died or were diagnosed between 1977 and 1981. From these, 3 episodes of cannibalistic feasts were identified, in each of which 2 or more participants were exposed to the infectious agent for the first time and died within weeks or months of each other 25–30 years later. Thus, it is shown that the natural incubation period of kuru could be as long as 25–30 years and is at times identical in 2 or more individuals infected at the same time, even over this span of years; also it is not determined by age at exposure. Further analysis of the episodes supports the concept on which the study was based, namely the transmission of kuru at the time of cannibalistic mourning with primary infection often occurring in infancy or early childhood.
© 1984 S. Karger AG, Basel
Article / Publication Details
Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.