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Original Papers

The Natural Incubation Period of Kuru and the Episodes of Transmission in Three Clusters of Patients

Klitzman R.L. · Alpers M.P. · Gajdusek D.C.

Author affiliations

Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea; National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, Md., USA

Related Articles for ""

Neuroepidemiology 1984;3:3–20

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Article / Publication Details

First-Page Preview
Abstract of Original Papers

Published online: January 11, 1985
Issue release date: 1984

Number of Print Pages: 18
Number of Figures: 0
Number of Tables: 0

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: https://www.karger.com/NED

Abstract

Epidemiological data were collected on the slow virus disease, kuru, among the Fore cultural and linguistic group in Papua New Guinea from 65 kuru patients who died or were diagnosed between 1977 and 1981. From these, 3 episodes of cannibalistic feasts were identified, in each of which 2 or more participants were exposed to the infectious agent for the first time and died within weeks or months of each other 25–30 years later. Thus, it is shown that the natural incubation period of kuru could be as long as 25–30 years and is at times identical in 2 or more individuals infected at the same time, even over this span of years; also it is not determined by age at exposure. Further analysis of the episodes supports the concept on which the study was based, namely the transmission of kuru at the time of cannibalistic mourning with primary infection often occurring in infancy or early childhood.

© 1984 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Papers

Published online: January 11, 1985
Issue release date: 1984

Number of Print Pages: 18
Number of Figures: 0
Number of Tables: 0

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: https://www.karger.com/NED


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