Respiration
Clinical Investigations
Variability of Exhaled Breath Condensate pH in Lung Transplant RecipientsCzebe K.a · Kullmann T.b · Csiszer E.a · Barat E.b · Horvath I.b · Antus B.a, baDepartment of Pulmonology and bDepartment of Pathophysiology, National Koranyi Institute for TB and Pulmonology, Budapest, Hungary
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Article / Publication Details
Received: June 05, 2007
Accepted: October 02, 2007
Published online: November 28, 2007
Issue release date: March 2008
Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 1
ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)
For additional information: https://www.karger.com/RES
Abstract
Background: Measurement of pH in exhaled breath condensate (EBC) may represent a novel method for investigating airway pathology. Objectives: The aim of this longitudinal study was to assess the variability of EBC pH in stable lung transplant recipients (LTR). Methods: During routine clinical visits 74 EBC pH measurements were performed in 17 LTR. EBC pH was also measured in 19 healthy volunteers on four separate occasions. EBC pH was determined at standard CO2 partial pressure by a blood gas analyzer. Results: Mean EBC pH in clinically stable LTR and in controls was similar (6.38 ± 0.09 vs. 6.44 ± 0.16; p =nonsignificant). Coefficient of variation for pH in LTR and controls was 2.1 and 2.3%, respectively. The limits of agreement for between-visit variability determined by the Bland-Altman test in LTR and healthy volunteers were also comparable (–0.29 and 0.46 vs. –0.53 and 0.44). Conclusions: Our data suggest that the variability of EBC pH in stable LTR is relatively small, and it is similar to that in healthy nontransplant subjects.
© 2007 S. Karger AG, Basel
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External Resources
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Liu J, Thomas PS: Relationship between exhaled breath condensate volume and measurements of lung volumes. Respiration 2007;74:142–145.
External Resources
- Kullmann T, Barta I, Horvath I: Effect of freezing on exhaled breath condensate pH. Respir Med 2007;101:2566.
Article / Publication Details
Received: June 05, 2007
Accepted: October 02, 2007
Published online: November 28, 2007
Issue release date: March 2008
Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 1
ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)
For additional information: https://www.karger.com/RES
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