Ignoring Intermarker Linkage Disequilibrium Induces False-Positive Evidence of Linkage for Consanguineous Pedigrees when Genotype Data Is Missing for Any Pedigree MemberLi B. · Leal S.M.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Tex., USA
Dr. Suzanne M. Leal
Baylor College of Medicine, Department of Molecular and Human Genetics
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Missing genotype data can increase false-positive evidence for linkage when either parametric or nonparametric analysis is carried out ignoring intermarker linkage disequilibrium (LD). Previously it was demonstrated by Huang et al. [
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