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Original Paper

Frequency of Cardiovascular Risk Factors in Obese Children and Adolescents Referred to a Tertiary Care Center in Israel

Shalitin S.a, b · Phillip M.a, b

Author affiliations

aInstitute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, and bSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Horm Res 2008;69:152–159

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 30, 2007
Accepted: April 27, 2007
Published online: January 08, 2008
Issue release date: January 2008

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 4

ISSN: 1663-2818 (Print)
eISSN: 1663-2826 (Online)

For additional information: https://www.karger.com/HRP

Abstract

Aims: To establish the frequency of dyslipidemia in obese Israeli children and adolescents and its association with other cardiovascular disease (CVD) risk factors. Methods: Files of 262 patients (5.1–18.8 years) with BMI >95th percentile for age and gender were reviewed for anthropometric and biochemical parameters of CVD risk. Dyslipidemia and hypertension were defined as cut-off point ≧95th percentile of healthy children. Results: Compared to patients with normal lipid profile, dyslipidemic patients (n = 71) had significantly higher prevalence of fatty liver (p < 0.001), higher percent body fat (males, p = 0.044), and higher C-reactive protein (females, p = 0.001). There was no significant difference in age, BMI-SDS, or familial CVD-related disorders. The hypertensive patients (n = 137) were significantly older than the normotensive patients (p < 0.001), had higher percent body fat (p = 0.008), larger waist circumference (p < 0.001), and higher HOMA-IR (p < 0.001). There were no significant between-group differences in BMI-SDS. The most significant factors associated with CVD risk were waist circumference and insulin level. Conclusions: Obese Israeli children have high rates of CVD risk factors, most of them unrelated to BMI-SDS or age. Therefore, we recommend screening for them in obese children with increased waist circumference of any age to detect those who require more intense interventions.

© 2008 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 30, 2007
Accepted: April 27, 2007
Published online: January 08, 2008
Issue release date: January 2008

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 4

ISSN: 1663-2818 (Print)
eISSN: 1663-2826 (Online)

For additional information: https://www.karger.com/HRP


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