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Viral Antibodies in the Sera from Patients with Parkinson Disease

Marttila R.J. · Arstila P. · Nikoskelainen J. · Halonen P.E. · Rinne U.K.

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Departments of Neurology and Virology, University of Turku, Turku

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Eur Neurol 1977;15:25–33

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Article / Publication Details

First-Page Preview
Abstract of Paper

Received: December 28, 1975
Accepted: December 30, 1975
Published online: January 25, 2008
Issue release date: 1977

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE

Abstract

An assay of antibodies to 15 various viruses and mycoplasma pneumoniae was performed on the serum specimens from 441 patients with Parkinson disease and from 443 healthy controls matched by sex, age, and place of residence, or from a representative group of these matched pairs. The main finding was a higher herpes simplex complement-fixing antibody level in patients with Parkinson disease than in controls. Patients with Parkinson disease had higher herpes simplex antibody titers more often than did their matched controls, and the matched controls, respectively, had low titers more often than the patients. The mean herpes simplex antibody titer (log2) of the patients (4.9) was significantly higher than that of controls (4.6) (p < 0.01). This difference was also demonstrable when matched pairs were analysed for paired differences of herpes simplex antibody titers. For other viral CF and HI antibodies studied and for mycoplasma pneumoniae CF antibody, there were no significant differences either in the mean titers or in the distribution of individual titer values between the patients with Parkinson disease and the matched controls.

© 1977 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Paper

Received: December 28, 1975
Accepted: December 30, 1975
Published online: January 25, 2008
Issue release date: 1977

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE


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