Neuropsychobiology

Biological Psychology/Pharmacopsychology

Animal Models for Predicting Clinical Efficacy of Anxiolytic Drugs: Social Behaviour

File S.E.

Author affiliations

MRC Neuropharmacology Research Group, Department of Pharmacology, The School of Pharmacy, University of London, UK

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Neuropsychobiology 1985;13:55–62

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Article / Publication Details

First-Page Preview
Abstract of Biological Psychology/Pharmacopsychology

Published online: February 19, 2008
Issue release date: 1985

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: https://www.karger.com/NPS

Abstract

The behavioural, physiological and pharmacological validation of one animal test of anxiety, the social interaction test, is described in detail. The effects of anxiolytic and anxiogenic drugs, and manipulations of catecholaminergic and serotonergic pathways are considered. The test is able to distinguish anxiolytic from sedative effects and is not sensitive to the actions of antidepressants or neuroleptics.

© 1985 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Biological Psychology/Pharmacopsychology

Published online: February 19, 2008
Issue release date: 1985

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: https://www.karger.com/NPS


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