Hypnosis in the Treatment of Anticipatory Nausea and Vomiting in Patients Receiving Cancer ChemotherapyMarchioro G.a · Azzarello G.b · Viviani F.c · Barbato F.a · Pavanetto M.a · Rosetti F.b · Pappagallo G.L.b · Vinante O.b
Department of Oncology,aPsycho-Oncology Section and bMedical Oncology Division, Local Health Unit No. 13, Noale, and cDepartment of General Psychology, University of Padua, Italy
Do you have an account?
- Rent for 48h to view
- Buy Cloud Access for unlimited viewing via different devices
- Synchronizing in the ReadCube Cloud
- Printing and saving restrictions apply
Rental: USD 8.50
Cloud: USD 20.00
Aims and Background: In addition to nausea and vomiting following chemotherapy treatment, cancer patients can experience these side effects prior to a treatment session, the so-called anticipatory nausea and vomiting. As various psychological and neurophysiological aspects have been claimed to be implied in its etiopathogenesis, the present paper aims to shortly review the etiological, epidemiological and therapeutical assumptions on the topic, in particular the psychological-behavioral therapies. Patients and Methods: The present study was carried out on 16 consecutive adult cancer patients affected by chemotherapy-induced anticipatory nausea and vomiting who had received at least four treatment cycles. All of them were submitted to induction of relaxation followed by hypnosis. Results: In all subjects anticipatory nausea and vomiting disappeared, and major responses to chemotherapy-induced emesis control were recorded in almost all patients. Conclusions: The experience highlights the potential value of hypnosis in the management of anticipatory nausea and vomiting; furthermore, the susceptibility to anticipatory nausea and vomiting is discussed under the psychoanalytic point of view.
© 2000 S. Karger AG, Basel
- Krakoff I: Cancer chemotherapeutic agents. CA Cancer J Clin 1987;37:93–105.
- Coates A, Abraham S, Kaye SB, Sowerbutts T, Frewin C, Cox RM, Tattersel MH: On the receiving end: Patient perception of the side effects of cancer chemotherapy. Eur J Cancer Clin Oncol 1983;19:203–208.
Morrow GR, Black PM: Anticipatory nausea and vomiting side effects experienced by cancer patients undergoing chemotherapy treatment; in Osoba D (ed): Effect of Cancer on Quality of Life. Boca Raton, CRC Press, 1991, p 251.
- Andrykowski MA, Redd WH: Longitudinal analysis of the development of anticipatory nausea. J Consult Clin Psychol 1987;55:36–41.
Cella DF, Pratt A, Holland JC: Long-term conditioned nausea and anxiety persisting in cured Hodgkin’s patients after chemotherapy. Proc Ann Meet Am Soc Clin Oncol 1984;3:73.
- Nicholas DR: Prevalence of anticipatory nausea and emesis in cancer chemotherapy patients. J Behav Med 1982;5:461–463.
- Fetting JH, Wilcox PM, Iwata BA, Criswell EL, Bosmajian LS, Sheilder VR: Anticipatory nausea and vomiting in an ambulatory medical oncology population. Cancer Treat Rep 1983;67:1093–1098.
Morrow GR, Arseneau JC, Asbury RF, Bennett JM, Boros L: Anticipatory nausea and vomiting in chemotherapy patients. N Engl J Med 1982;306:431–432.
- Nesse RM, Carli T, Curtis GG, Kleinman PD: Pretreatment nausea in cancer chemotherapy: A conditioned response? Psychosom Med 1980;42:33–36.
- Nerenz DR, Leventhal H, Love RR: Anxiety and drug taste as predictors of anticipatory nausea in cancer chemotherapy. J Clin Oncol 1986;4:224–233.
- Wilcox PM, Fetting JH, Nettescheim KM, Abeloff MD: Anticipatory vomiting in women receiving cyclophosphamide, methotrexate and 5-FU (CMF) adjuvant chemotherapy for breast carcinoma. Cancer Treat Rep 1982;66:1601–1604.
- Morrow GR, Roscoe GA, Hynes HE, Flynn PJ, Pierce HI, Burish T: Progress in reducing anticipatory nausea and vomiting: A study of community practice. Support Care Cancer 1998;6:46–50.
- Morrow GR: Prevalence and correlates of anticipatory nausea and vomiting in chemotherapy patients. J Natl Cancer Inst 1982;68:585–588.
Boakes AR, Tarrier N, Barnes BW, Tattersall MHN: Prevalence of anticipatory nausea and other side-effects in cancer patients receiving chemotherapy. Eur J Cancer 1993;29A:866–870.
- Andrykowski MA, Jacobsen PB, Marks E, Garfinkle K, Hakes TB, Kaufman RJ, Currie VE, Holland JC, Redd WH: Prevalence, predictors and course of anticipatory nausea in women receiving adjuvant chemotherapy for breast cancer. Cancer 1988;62:2607–2613.
- Morrow GR, Lindke J, Black PM: Anticipatory nausea development in cancer patients: Replication and extension of a learning model. Br J Psychol 1991;82:61–72.
Morrow GR: Clinical characteristics associated with the development of anticipatory nausea and vomiting in cancer patients undergoing chemotherapy treatment. J Clin Oncol 1984;10:1170–1176.
- Montgomery GH, Bovbjerg DH: The development of anticipatory nausea in patients receiving adjuvant chemotherapy for breast cancer. Physiol Behav 1997;61:737–741.
- Morrow GR, Roscoe JA, Kirshner JJ, Rosenbluth RJ: Anticipatory nausea and vomiting in the era of 5-HT3 antiemetics. Support Care Cancer 1998;6:244–247.
- van Komen RW, Redd WH: Personality factors asociated with anticipatory nausea/vomiting in patients receiving cancer chemotherapy. Health Psychol 1985;4:189–202.
Morrow GR: Susceptibility to motion sickness and the development of anticipatory nausea and vomiting in cancer patients undergoing chemotherapy. Cancer Treat Rep 1984;68:99–100.
- Andrykowski MA: Do infusion-related tastes and odours facilitate the development of anticipatory nausea? A failure to support hypothesis. Health Psychol 1987;6:329–341.
Chin SB, Kucuk O, Peterson R, Ezdinli EZ: Variables contributing to anticipatory nausea and vomiting in cancer chemotherapy. J Dev Behav Pediatr 1997;15:262–267.
Tyc VL, Mulhem RK, Bieberich AA: Anticipatory nausea and vomiting in pediatric cancer patients: An analysis of conditioning and coping variables. Am J Clin Oncol 1992;18:27–33.
- Montgomery GH, Tomoyasu N, Bovbjerg DH, Andrykowski MA, Currie VE, Jacobsen PB, Redd WH: Patients’ pretreatment expectations of chemotherapy-related nausea are an independent predictor of anticipatory nausea. Ann Behav Med 1998;20:104–109.
Morrow GR, Dobkin PL: Anticipatory nausea and vomiting in cancer patients undergoing chemotherapy treatment: Prevalence, etiology and behavioural interventions. Clin Psychol Rev 1988;8:517–556.
- Addelmann M, Erlichman C, Fine S, Warr D, Murray C: Phase I/II trial of BRL43694: A novel 5-HT3 antagonist for the prevention of chemotherapy-induced nausea and vomiting. J Clin Oncol 1990;8:337–341.
- Olafsdottir R, Sjoden PO, Westling B: Prevalence and prediction of chemotherapy related anxiety, nausea and vomiting in cancer patients. Behav Res Ther 1986;24:59–66.
- Andrykowski MA: The role of anxiety in the development of anticipatory nausea in cancer chemotherapy: A review and synthesis. Psychosom Med 1990;52:458–475.
- Watson M, Meyer L, Thomson A, Osofsky S: Psychological factors predicting nausea and vomiting in breast cancer patients on chemotherapy. Eur J Cancer 1998;34:831–837.
- Burish TG, Carey MP: Conditioned aversive responses in cancer chemotherapy patients. Theoretical and developmental analysis. J Consult Clin Psychol 1986;54:593–600.
- Watson M: Anticipatory nausea and vomiting: Broadening the scope of psychological treatments. Support Care Cancer 1993;1:171–177.
Black PM, Morrow GR: Anticipatory nausea and emesis: Behavioural interventions; in Watson M (ed): Cancer Patient Care: Psychological Treatment Methods. London, BPS/Cambridge University Press, 1991, pp 45–75.
King CR: Nonpharmacologic management of chemotherapy-induced nausea and vomiting. Oncol Nurs Forum 1997;24:41–48.
- Larbig W: Psycho-oncologic interventions – Critical review. Psychother Psychosom Med Psychol 1998;48:381–389.
- Andrykowski MA, Redd WH, Hatfield AK: Development of anticipatory nausea: A prospective analysis. J Consult Clin Psychol 1985;53:447–454.
- Aapro MS, Kirchner V, Terrey JP: The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: The effect of granisetron. Br J Cancer 1994;69:957–960.
- Lyles JN, Burish TG, Krozely MG, Oldham RK: Efficacy of relaxation training and guided imagery in reducing the aversiveness of cancer chemotherapy. J Consult Clin Psychol 1982;50:509–524.
- Burish TG, Carey MP, Krozely MG, Greco FA: Conditioned side effects induced by cancer chemotherapy: Prevention through behavioral treatment. J Consult Clin Psychol 1987;55:42–48.
- Morrow GR, Morrell C: Behavioral treatment for the anticipatory nausea and vomiting induced by cancer vomiting. N Engl J Med 1982;307:1476–1480.
Cotanch P, Hockenberry M, Herman S: Self-hypnosis as antiemetic therapy in children receiving chemotherapy. Oncol Nurs Forum 1985;12:41–46.
Granone F: Trattato di ipnosi. Torino, Boringhieri, 1972, pp 93–126.
Erickson MH: Advanced Techniques of Hypnosis and Therapy. New York, Grune & Stratton, 1967, pp 28–85.
Marchioro G, Azzarello G, Checchin F, Perale M, Segati R, Sampognaro E, Rosetti F, Franchin A, Pappagallo GL, Vinante O: The impact of a psychological intervention on quality of life in non-metastatic breast cancer. Eur J Cancer 1996;32A:1612–1615.
Marchioro G, Checchin F, Perale M, Azzarello G, Segati R, Franchin A, Vinante O: Personality and intimate relationship of patients affected by gynecological tumors. Preliminary results. Proc XVI Int Cancer Congr 1994, vol 3, pp 2251–2254.
Freud S (1892): Opere. Torino, Boringhieri, 1989, vol 1, pp 123–133.
Article / Publication Details
Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.