Brain, Behavior and Evolution
Original Paper
The Pontocerebellar System in the Opossum, Didelphis virginiana; pp. 179–192A Horseradish Peroxidase Study
Mihailoff G.A. · Martin G.F. · Linauts M.
Department of Cell Biology, University of Texas Health Science Center, Dallas, Tex.
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Article / Publication Details
Published online: March 19, 2008
Issue release date: 1980
Number of Print Pages: 14
Number of Figures: 0
Number of Tables: 0
ISSN: 0006-8977 (Print)
eISSN: 1421-9743 (Online)
For additional information: https://www.karger.com/BBE
Abstract
The method of retrograde axonal transport of horseradish peroxidase was employed to demonstrate certain organizational features of the pontocerebellar system in adult opossums. The spinal cerebellum (anterior lobe, pyramis and paramedian lobule) receives input from neurons situated in ventral and lateral regions throughout the rostro-caudal extent of the pons. The projection to the anterior lobe and pyramis was primarily contralateral, whereas the projection to the paramedian lobule included a substantial ipsilateral contribution. The pontine projection to the vermal visual-auditory area was also found to include significant bilateral components which were observed to be organized in mirror image locations in medial, ventral and lateral regions. The paraflocculus was found to receive input from a relatively large number of pontine neurons, the medial injection producing a more bilateral distribution of labeled neurons while the lateral injection resulted in primarily contralateral labeling. Crus I and crus II of the cerebellar hemispheres received a bilateral projection which also included neurons distributed in mirror image locations in both halves of the pontine gray. Taken together such observations indicate that the pontocerebellar system includes a more substantial ipsilateral contribution than has heretofore been recognized. In addition, comparison of the locations of various groups of labeled neurons resulting from spatially separate injection sites suggests the possibility that some pontocerebellar neurons might diverge to reach more than one cerebellar zone, i.e. cells in a similar ventrolateral pontine region were labeled following injections in the anterior lobe, pyramis and crus I. Evidence for convergence of multiple pontine areas to single cerebellar foci was not as compelling.
© 1980 S. Karger AG, Basel
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Article / Publication Details
Published online: March 19, 2008
Issue release date: 1980
Number of Print Pages: 14
Number of Figures: 0
Number of Tables: 0
ISSN: 0006-8977 (Print)
eISSN: 1421-9743 (Online)
For additional information: https://www.karger.com/BBE
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