Neuroendocrinology
Original Paper
Adaptation of the Adrenocortical Response during Repeated Stress in Thalamic PigeonsRamade F. · Baylé J.-D.Laboratory of Neuroendocrinology B, University of Montpellier II, France
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Article / Publication Details
Received: November 07, 1983
Accepted: February 22, 1984
Published online: March 28, 2008
Issue release date: 1984
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 0028-3835 (Print)
eISSN: 1423-0194 (Online)
For additional information: https://www.karger.com/NEN
Abstract
Chronic vascular catheterization allowed to obtain serial blood samples before and after stress application to thalamic pigeons. Daily repetition of the same stress, at the same hour, for 5 weeks led to drastic changes in the stress-induced adrenocortical reaction. The rebounding, long-lasting rise in plasma corticosterone occurring after initial presentation of electrical footshocks was replaced by a single peak of corticosterone, lower and shorter than the initial response. Moreover, an anticipatory conditioned rise in corticosterone appeared before stress. Random distribution of stressful stimuli, thrice a day, for 5 weeks resulted in the single peak pattern of post-stress adrenocortical reaction, without any anticipatory component. When electrical footshocks were omitted after 5 weeks of daily regular presentation of stress, only the anticipatory peak in plasma corticosterone occurred. Shifting the daily lighting from the usual 06.00 a.m. to 04.00 a.m. led to a shift in the anticipatory conditioned endocrine response which appeared 2 h sooner than usual. Thalamic involvement in the process of adaptation to chronic stress is discussed.
© 1984 S. Karger AG, Basel
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Article / Publication Details
Received: November 07, 1983
Accepted: February 22, 1984
Published online: March 28, 2008
Issue release date: 1984
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 0028-3835 (Print)
eISSN: 1423-0194 (Online)
For additional information: https://www.karger.com/NEN
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