Annals of Nutrition and Metabolism

Original Paper

Traditional Fermentation Increases Goitrogenic Activity in Pearl Millet

Elnour A.a · Liedén S.-Å.a · Bourdoux P.b · Eltom M.c · Khalid S.A.d · Hambraeus L.a

Author affiliations

a Department of Medicine Nutrition, Uppsala University, Uppsala, Sweden; b Laboratory of Pediatrics, Free University of Brussels, Belgium; c Omdurman Nutrition and Endocrinology Research Center, Omdurman, and d Department of Pharmacognosy, Faculty of Pharmacy, University of Khartoum, Sudan

Keywords: MilletFermentationGoitrogenMineralsSudan

Related Articles for ""
Ann Nutr Metab 1998;42:341–349
https://doi.org/10.1159/000012754

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: January 20, 1999
Issue release date: November – December

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 4

ISSN: 0250-6807 (Print)
eISSN: 1421-9697 (Online)

For additional information: https://www.karger.com/ANM

Abstract

Epidemiological evidence suggests that millet might play a role in the etiology of endemic goiter. Recently, we showed that a traditional fermentation procedure of two pearl millet (Pennisetum americanum L. Lecke) cultivars grown in Sudan modified their effects on the weight of the thyroid gland and thyroid hormone profile in rats. In the present study, we report that this fermentation procedure reduced the ash contents of millet by about 40% and removed considerable amounts of Mg (>50%), Zn (27–39%) and K (45%). Other minerals (Ca, Fe, Cu) were not affected. Feeding of one fermented cultivar resulted in significant reduction in bone Mg and Zn contents, whereas feeding of the other fermented cultivar resulted in reduction of bone Mg only. Dietary Mg intake and bone Mg contents correlated negatively with serum T3. Groups fed the millet diets had higher serum Se level compared to those fed wheat or casein diets and feeding of fermented millet resulted in a further increase in serum Se level. Thus our data indicate that in rats the enhanced effects of millet on the thyroid induced by fermentation is likely related to removal of minerals from millet and/or chemical transformation of the goitrogens contained in millet.



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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: January 20, 1999
Issue release date: November – December

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 4

ISSN: 0250-6807 (Print)
eISSN: 1421-9697 (Online)

For additional information: https://www.karger.com/ANM

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1998, Vol.42, No. 6

November – December

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