European Surgical Research
Original Paper
Biological Tolerance to Polydioxanone Absorbable Clips: A Comparison with Metallic Ligating ClipsMichel F.a · Ponsot Y.a · Roland J.b · Thibault Ph.a · Rouquette A.M.c · Gattegno B.aaService d’Urologie, bService Central d’Anatomopathologie, cService d’Hématologie Biologique, Hôpital Tenon, Paris, France
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Article / Publication Details
Received: October 30, 1984
Accepted: February 18, 1985
Published online: April 18, 2008
Issue release date: 1985
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0014-312X (Print)
eISSN: 1421-9921 (Online)
For additional information: https://www.karger.com/ESR
Abstract
An experiment was conducted in 96 rats to determine the tissue tolerance to a hemostatic and absorbable clip made of polydioxanone, as compared to standard metallic clips. Clinical tolerance was similar and no bleeding or death occurred because of the material. Pathological studies showed a mild histiocytic reaction with absorbable clips and a stronger inflammatory reaction with metallic clips. This experiment indicates that absorbable clips are efficient and well tolerated and we strongly recommend the use of this material.
© 1985 S. Karger AG, Basel
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Article / Publication Details
Received: October 30, 1984
Accepted: February 18, 1985
Published online: April 18, 2008
Issue release date: 1985
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0014-312X (Print)
eISSN: 1421-9921 (Online)
For additional information: https://www.karger.com/ESR
Copyright / Drug Dosage / Disclaimer
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