European Surgical Research
Original Paper
Collagen in Surgical ResearchKlopper P.J.Laboratory for Experimental Surgery, Academic Hospital, University of Amsterdam, The Netherlands
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Article / Publication Details
Accepted: December 12, 1985
Published online: April 22, 2008
Issue release date: 1986
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 0014-312X (Print)
eISSN: 1421-9921 (Online)
For additional information: https://www.karger.com/ESR
Abstract
Collagen plays an important role in the final result of surgical intervention. For years, surgical catgut has been an irreplaceable suture material. Since the last decade, synthetic materials have gained ground. Healing of the intestinal wound is dependent on the repair of the epithelium, but the process takes place only if the collagen of the submucosal layer is such that epithelial cells can cover it. Surgical technique influences this process, and considerable progress is made by the use of mechanical devices as demonstrated by our own experiments. In the last years, a revival of collagen as biomaterial has been observed. Experiments in dogs showed that several applications are of interest. The matrix of processed natural collagen can support the repair of connective tissue in the host. In the near future, the competition between synthetic material and collagen in natural or reconstituted form will be continued and open new fields of research.
© 1986 S. Karger AG, Basel
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Article / Publication Details
Accepted: December 12, 1985
Published online: April 22, 2008
Issue release date: 1986
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 0014-312X (Print)
eISSN: 1421-9921 (Online)
For additional information: https://www.karger.com/ESR
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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