Cytogenetic and Genome Research

Original Article

Deletion of the centromere as a mechanism for achieving stability of a dicentric chromosome

Vianna-Morgante A.M. · Rosenberg C.

Author affiliations

Departamento de Biologia, Instituto de Biociências, Universidadc de São Paulo, São Paulo

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Cytogenet Cell Genet 1986;42:119–122

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Article / Publication Details

First-Page Preview
Abstract of Original Article

Accepted: November 12, 1985
Published online: May 08, 2008
Issue release date: 1986

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: https://www.karger.com/CGR

Abstract

A patient with primary amenorrhea and a terminal rearrangement of chromosomes 13 and 20 is described. The stability of the dicentric translocation chromosome was achieved by suppression of the activity of the centromere of chromosome 20 and actual deletion of the centromere of chromosome 13. These two mechanisms may be fundamentally similar if centromere inactivation results from a visually undetectable deletion.

© 1986 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Article

Accepted: November 12, 1985
Published online: May 08, 2008
Issue release date: 1986

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: https://www.karger.com/CGR


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