Gene Mapping, Cloning, and Sequencing
Regional localization of the human platelet-derived endothelial cell growth factor (ECGF1) gene to chromosome 22q13Stenman G.a · Sahlin P.a · Dumanski JP.bc · Hagiwara K.d · Ishikawa F.d · Miyazono K.e · Collins VP.b · Heldin C.-H.e
aLaboratory of Cytogenetics, Department of Oral Pathology, University of Göteborg, Göteborg (Sweden); bLudwig Institute for Cancer Research, Stockholm Branch, Stockholm (Sweden); cDepartment of Clinical Genetics, Karolinska Hospital, Stockholm (Sweden); dThe Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Tokyo (Japan); and eLudwig Institute for Cancer Research, Uppsala Branch, Biomedical Center, Uppsala (Sweden)
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Using in situ hybridization and a panel of human × rodent somatic cell hybrids, which discriminates between four different regions of human chromosome 22, we have localized the gene for human platelet-derived endothelial cell growth factor (ECGFl) to 22q13, placing ECGFl distal to the PDGFB locus at 22q12.3→q13.1.
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