Cytogenetic and Genome Research

Animal Cytogenetics anad Comparative Mapping

Regional mapping of the Rowett nude gene (RONU) to rat chromosome 10q24→q32 by localizing linked SYB2 and GH loci

Kuramoto T. · Serikawa T. · Hayasaka N. · Mori M. · Yamada J.

Author affiliations

Institute of Laboratory Animals, Faculty of Medicine, Kyoto University, Kyoto (Japan)

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Cytogenet Cell Genet 1993;63:107–110

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Article / Publication Details

First-Page Preview
Abstract of Animal Cytogenetics anad Comparative Mapping

Accepted: August 17, 1992
Published online: May 14, 2008
Issue release date: 1993

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: https://www.karger.com/CGR

Abstract

The Rowett nude gene (RONU) has been mapped on rat chromosome (Chr) 10 by linkage analysis using (ACI × F344/N-RONU/RONU)F1 × F344/N-RONU/RONU backcrossprogeny. The gene order on the chromosome was RR92 -(16.1 cM) – RR24 – (17.9 cM) – MYHSE (myosin heavy chain, embryonic) – (1.0 cM) – SYB2 (synaptobrevin 2) – (1.0 cM) -SHBG (sex hormone-binding globulin) – (4.0 cM) – RONU (Rowett nude) – (29.0 cM) – AEP (anion exchange protein), PPY (pancreatic polypeptide) – (3.0 cM) – ACE (angiotensin I converting enzyme), GH (growth hormone). The RONU locus was localized to 10q24→q32 by fluorescence in situ hybridization of the closely linked SYB2 and loosely linked GH loci on the opposite side. Conserved linkage of homologous loci mapped to rat Chr 10 and mouse Chr 11 supports the hypothesis that the RONU locus is a rat homolog of the mouse nu locus.

© 1993 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Animal Cytogenetics anad Comparative Mapping

Accepted: August 17, 1992
Published online: May 14, 2008
Issue release date: 1993

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: https://www.karger.com/CGR


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