Cytogenetic and Genome Research
Animal Cytogenetics and Comparative Mapping
Genome distribution, chromosomal allocation, and organization of the major and minor satellite DNAs in 11 species and subspecies of the genus MusGaragna S.a · Redi C.A.a · Capanna E.b · Andayani N.c · Alfano R.M.d · Doi P.d · Viale G.daDipartimento di Biología Animale and Centra di Studio per l’lstochimica del CNR, Universitá di Pavia, Pavia (Italy); bDipartimento di Biología Animale e dell’Uomo, Universitá “La Sapienza” Roma, Rome (Italy); cDepartment of Biology, University of Indonesia, Depok (Indonesia); and dIstituto di Anatomia e Istologia Patologica II, Universitá di Milano, Milan(Italy)
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Article / Publication Details
Accepted: September 30, 1992
Published online: May 14, 2008
Issue release date: 1993
Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0
ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)
For additional information: https://www.karger.com/CGR
Abstract
We compared the genome distribution, chromosomal allocation, and organization of the major and minor satellite DNAs (satDNAs) in 11 species and subspecies of the genus Mus. Southern blot analysis of the major and minor satDNAs showed similar fragment profiles in all 11 species, with the exception of M. cervicolor and M. cookii for the major satDNAs and M. caroli, M. cervicolor, and M. cookii for the minor satDNAs, where these sequences could not be detected by the probes used. In situ hybridization of the major and minor satDNA probes revealed chromosome-specific allocations of these sequences with quantitative species-specific patterns. Fluorometric analysis of the organization of the satellite sequences suggested that in the M. domesticus genome satDNA sequences are clustered in tandem repeats that are longer than those present in other Mus genomes. When compared with the other Mus genomes so far studied, the domesticus genome shows the highest quantity of satDNA sequences with a long-range organization of satDNA sequences.
© 1993 S. Karger AG, Basel
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Article / Publication Details
Accepted: September 30, 1992
Published online: May 14, 2008
Issue release date: 1993
Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0
ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)
For additional information: https://www.karger.com/CGR
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