Cytogenetic and Genome Research
Gene Mapping, Cloning, and Sequencing
Regional mapping of the human NSP gene to chromosome region 14q21→q22 by fluorescence in situ hybridization analysisKools P.F.J.a · Roebroek A.J.M.a · van de Velde H.J.K.a · Marynen P.a · Bullerdiek J.b · Van de ven W.J.M.aaCenter for Human Genetics, University of Leuven, Leuven (Belgium), and bCenter for Human Genetics, University of Bremen, Bremen (Germany)
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Article / Publication Details
Accepted: May 13, 1993
Published online: May 15, 2008
Issue release date: 1994
Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0
ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)
For additional information: https://www.karger.com/CGR
Abstract
Genetic sequences of the novel NSP gene, which encodes neuroendocrine-specific proteins, were isolated from cDNA libraries constructed with mRNA isolated from human lung carcinoma cells. Hybridization analysis of a panel of human × mouse cell hybrids with an 0.8-kb NSP cDNA probe indicated that the human NSP gene is probably located on chromosome 14. Fluorescence in situ hybridization analysis of metaphase chromosomes using overlapping genomic clones of NSP as a probe localized the NSP gene to chromosome region 14q21→q22.
© 1994 S. Karger AG, Basel
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Article / Publication Details
Accepted: May 13, 1993
Published online: May 15, 2008
Issue release date: 1994
Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0
ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)
For additional information: https://www.karger.com/CGR
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