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Gene Mapping, Cloning, and Sequencing

The gene encoding myeloid α-3-fucosyltransferase (FUT4) is located between D11S388 and D11S919 on 11q21

Reguigne I.a · James M.R.b · Richard III C.W.c · Mollicone R.a · Seawright A.d · Lowe J.B.e · Oriol R.a · Couillin P.a

Author affiliations

aNSERM U178, Villejuif Cedex (France); bINSERM U358 and CEPH, Paris (France); cDepartments of Psychiatry and Human Genetics, University of Pittsburgh, Pittsburgh PA (USA); dMRC Human Genetics Unit, Western General Hospital, Edinburgh (UK); and eHoward Hughes Medical Institute, Ann Arbor MI (USA)

Related Articles for ""

Cytogenet Cell Genet 1994;66:104–106

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Article / Publication Details

First-Page Preview
Abstract of Gene Mapping, Cloning, and Sequencing

Accepted: June 02, 1993
Published online: May 15, 2008
Issue release date: 1994

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: https://www.karger.com/CGR

Abstract

The last step in the biosynthesis of Lex antigen, the addition of a fucose to precursor polysaccharides, can be catalyzed by different α-3-fucosyltransferases. We localized the gene (FUT4) encoding myeloid α-3-fucosyltransferase by PCR assay using panels of somatic cell and radiation hybrids which retain different rearrangements of chromosome 11. FUT4 was assigned to chromosome band 11q21 between D11S388 and D11S919.

© 1994 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Gene Mapping, Cloning, and Sequencing

Accepted: June 02, 1993
Published online: May 15, 2008
Issue release date: 1994

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: https://www.karger.com/CGR


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