Animal Cytogenetics and Comparative Mapping
Assignment of the gene for beta-casein (CSN2) to 4q13→q21 in humans and 3p13→p12 in chimpanzeesMcConkey E.H.a · Menon R.a,b · Williams G.a · Baker E.c · Sutherland G.R.c
aDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO (USA); bGalaGen, Inc., North Arden Hills, MN (USA); and cDepartment of Cytogenetics and Molecular Genetics, Adelaide Children’s Hospital, North Adelaide, South Australia (Australia)
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The human beta-casein gene (CSN2) has been mapped by fluorescence in situ hybridization to human chromosome 4q13→q21 and to the homologous chimpanzee chromosome at 3p13→p12. This confirms the presence of a pericentric inversion that distinguishes the two species, as first observed by chromosomal banding studies.
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