Differential Impact of Lower Urinary Tract Symptoms on Generic and Disease-Specific Quality of Life in Men and WomenAraki I.a · Tsuchida T.a · Nomura T.a · Fukasawa M.a · Takihana Y.a · Koyama N.b · Takeda M.a
aDepartment of Urology, Faculty of Medicine, University of Yamanashi, Chuo, and bClinical Pharmacology and Biostatistics Department, Sankyo Co. LTD., Tokyo, Japan
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Introduction: We investigated how generic and disease-specific measures differ in estimating the quality of life (QoL) impact of lower urinary tract symptoms (LUTS). Materials and Methods: A total of 172 men and 67 women ≧40 years old who attended the public lectures completed the questionnaire comprising the International Prostate Symptom Score, benign prostatic hyperplasia impact index and SF-36 Health Survey. The multiple regression analysis was performed to evaluate the QoL impact of LUTS. Results: Both storage and voiding symptoms showed significant correlations with disease-specific QoL. Among men, voiding symptom correlated more closely with disease-specific QoL than storage symptom did, and this finding was reversed among women. Storage but not voiding symptoms showed a significant correlation with generic QoL. Among men, storage symptom correlated more closely with mental health than physical health, and the reversed finding was obtained among women. Generic QoL, especially physical health, was significantly influenced by some comorbid diseases, but disease-specific QoL was not. Conclusions: The QoL impact of LUTS was differentially estimated by disease-specific and generic measures with sex differences.
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- Hunter DJW, McKee M, Black NA, Sanderson CFB: Health status and quality of life of British men with lower urinary tract symptoms: results from SF-36. Urology 1995;45:962–971.
- Peters TJ, Donovan JL, Kay HE, Abrams P, De La Rosette JJMCH, Porru D, Thüroff JW, the International Continence Society ‘Benign Prostatic Hyperplasia’ Study Group: The International Continence Society ‘Benign Prostatic Hyperplasia’ Study: the bothersomeness of urinary symptoms. J Urol 1997;157:885–889.
- Girman CJ, Jacobsen SJ, Tsukamoto T, Richard F, Garraway WM, Sagier P-P, Guess HA, Rhodes T, Boyle P, Lieber MM: Health-related quality of life associated with lower urinary tract symptoms in four countries. Urology 1998;51:428–436.
- Schatzl G, Temml C, Waldmüller J, Thürridl T, Haidinger G, Madersbacher S: A comparative cross-sectional study of lower urinary tract symptoms in both sexes. Eur Urol 2001;40:213–219.
- Okamura K, Usami T, Nagahama K, Maruyama S, Mizuta E: The relationships among filling, voiding subscores from International Prostate Symptom Score and quality of life in Japanese elderly men and women. Eur Urol 2002;42:498–505.
- Welch G, Weinger K, Barry MJ: Quality of life of lower urinary tract symptom severity: results from the Health Professionals Follow-up Study. Urology 2002;59:245–250.
- Boyle P, Robertson C, Mazzeta C, Keech M, Hobbs R, Fourcade R, Kiemeney L, Lee C, the UrEpik Study Group: The relationship between lower urinary tract symptoms and health status: the UREPIK study. BJU Int 2003;92:575–580.
- Masumori N, Homma D, Tsukamoto T: Web-based research of lower urinary tract symptoms that affect quality of life in elderly Japanese men: analysis using a structural equation model. BJU Int 2005;95:1013–1022.
Barry MJ, Batista JE, Donovan J, Jonas U, Kurth KH, Lukacs B, Norman R, O’Leary M, Prezioso D, Richard F, Tsukamoto T: Measuring the symptoms and health impact of benign prostatic hyperplasia and its treatment; in Chatelain C, Denis L, Foo KT, Khoury S, Mc Connell J (eds): Benign Prostatic Hyperplasia. 5th International Consultation on Benign Prostatic Hyperplasia (BPH). Plymouth, Plymbridge, 2000, pp 201–225.
- Barry MJ, Fowler FJ, O’Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK, the Measurement Committee of the American Urological Association: Measuring disease-specific health status in men with benign prostatic hyperplasia. Med Care 1995;33:AS145–AS155.
- Barry MJ: Evaluation of symptoms and quality of life in men with benign prostatic hyperplasia. Urology 2001;58(suppl 6A):25–32.
- Ware JE, Gandek B: Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) Project. J Clin Epidemiol 1998;51:903–912.
- Araki I, Zakoji H, Komuro M, Furuya Y, Fukasawa M, Takihana Y, Takeda M: Lower urinary tract symptoms in men and women without underlying disease causing micturition disorder: a cross-sectional study assessing the natural history of bladder function. J Urol 2003;170:1901–1904.
- Terai A, Matsui Y, Ichioka K, Ohara H, Terada N, Yoshimura K: Comparative analysis of lower urinary tract symptoms and bother in both sexes. Urology 2004;63:487–491.
- Welch G, Kawachi I, Barry MJ, Giovannucci E, Colditz GA, Willett WC: Distinction between symptoms of voiding and filling in benign prostatic hyperplasia: findings from the Health Professionals Follow-up Study. Urology 1998;51:422–427.
- Alonso J, Ferrer M, Gandek B, Ware JE Jr, Aaronson NK, Mosconi P, Rasmussen NK, Bullinger M, Fukuhara S, Kaasa S, Leplège A, the IQOLA Project Group: Health-related quality of life associated with chronic conditions in eight countries: results from the International Quality of Life Assessment (IQOLA) Project. Qual Life Res 2004;13:283–298.
- Ware JE Jr, Gandek B, Koshinski M, Aaronson NK, Apolone G, Brazier J, Bullinger M, Kaasa S, Leplège A, Prieto L, Sullivan M, Thunedborg K: The equivalence of SF-36 summary health scores estimated using standard and country-specific algorithms in 10 countries: results from IQOLA Project. J Clin Epidemiol 1998;51:1167–1170.
- Ware JE Jr, Kosinski M, Bayliss MS, McHorney CA, Rogers WH, Raczek A: Comparison of methods for the scoring and statistical analysis of SF-36 Health Profile and summary measures: summary of results from the Medical Outcomes Study. Med Care 1995;33:AS264–AS279.
Fukuhara S, Suzukama Y, Bito S, Kurokawa K: Manual of SF-36 Japanese Version 1.2. Tokyo, Public Health Research Foundation, 2001.
- Eckhardt MD, van Venrooij GEPM, van Melick HHE, Boon TA: Prevalence and bothersomeness of lower urinary tract symptoms in benign prostatic hyperplasia and their impact on well-being. J Urol 2001;166:563–568.
- Mozes B, Maor Y, Shmueli A: The competing effects of disease states on quality of life of the elderly: the case of urinary symptoms in men. Qual Life Res 1999;8:93–99.
- Coyne KS, Zhou Z, Thompson C, Versi E: The impact on health-related quality of life of stress, urge and mixed urinary incontinence. BJU Int 2003;92:731–735.
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