Controversies in the Treatment of Prostate Cancer

10th International Symposium on Special Aspects of Radiotherapy, Berlin, September 2006

Editor(s): Moser, L. (Berlin)
Schostak, M. (Berlin)
Miller, K. (Berlin)
Hinkelbein, W. (Berlin)

Lymph Node-Positive Prostate Cancer

Lymphadenectomy in Prostate Cancer

Radio-Guided Lymph Node Mapping: An Adequate Staging Method
Winter A. ยท Wawroschek F.

Author affiliations

Department of Urology, Klinikum Oldenburg, Oldenburg , Germany

Related Articles for ""

Moser L, Schostak M, Miller K, Hinkelbein W (eds): Controversies in the Treatment of Prostate Cancer. Front Radiat Ther Oncol. Basel, Karger, 2008, vol 41, pp 58-67

Log in to MyKarger to check if you already have access to this content.


Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

CHF 38.00 *
EUR 35.00 *
USD 39.00 *

Select

KAB

Buy a Karger Article Bundle (KAB) and profit from a discount!


If you would like to redeem your KAB credit, please log in.


Save over 20% compared to the individual article price.

Learn more

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00

Select

Complete book

  • Immediate access to all parts of this book
  • Cover-to-cover formats may be available
  • Unlimited re-access via MyKarger
  • Unrestricted printing, no saving restriction for personal use
read more

Pricing depends on hard-cover price


Select

* The final prices may differ from the prices shown due to specifics of VAT rules.

Article / Publication Details

First-Page Preview
Abstract of Lymph Node-Positive Prostate Cancer

Published online: June 11, 2008
Cover Date: 2008

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0

ISBN: 978-3-8055-8524-8 (Print)
eISBN: 978-3-8055-8525-5 (Online)

Abstract

Lymph node status in prostate cancer is not only of prognostic but also of tremendous therapeutic relevance. In case of positive lymph nodes (N+), common standards demand the renunciation of local curative therapy (such as radiotherapy or radical prostatectomy) and hormonal withdrawal, or an appropriate adjuvant therapy can be planned (for example, early androgen ablation). But none of the currently available means of radiologic imaging (CT, MRT, PET-CT) provides sufficient identification of lymph node (micro)metastases ( < 5 mm). Also, predictive nomograms which are based on data from limited pelvic lymph node dissection (PLND) do not offer a sufficient grade of reliability. However, the limitation of the dissection area results in missing about 50-60% of N+ patients. In addition, the preoperative diagnostics often underestimate the true pathological stage. Presently, it seems that only the histological detection of lymph node metastases by methods with high sensitivity, like sentinel lymph node dissection or extended PLND, are suitable for lymph node staging in prostate cancer. The disadvantages of extended PLND are a high operative effort and increased complication rate. Therefore, sentinel lymph node dissection seems to strike a balance between high sensitivity and low complication rate.




Related Articles:


Article / Publication Details

First-Page Preview
Abstract of Lymph Node-Positive Prostate Cancer

Published online: June 11, 2008
Cover Date: 2008

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0

ISBN: 978-3-8055-8524-8 (Print)
eISBN: 978-3-8055-8525-5 (Online)


Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
TOP