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Review Article

Reproductive Biology in Egg-Laying Mammals

Grützner F.a · Nixon B.b · Jones R.C.b

Author affiliations

aSchool of Molecular & Biomedical Science, The University of Adelaide, bDiscipline of Biological Sciences, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, Australia

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Sex Dev 2008;2:115–127

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Article / Publication Details

First-Page Preview
Abstract of Review Article

Received: May 07, 2008
Accepted: June 09, 2008
Published online: September 03, 2008
Issue release date: September 2008

Number of Print Pages: 13
Number of Figures: 6
Number of Tables: 0

ISSN: 1661-5425 (Print)
eISSN: 1661-5433 (Online)

For additional information: https://www.karger.com/SXD

Abstract

The duck-billed platypus and short-beaked echidna are iconic species in Australia. Their morphology and physiology have puzzled scientists all over the world for more than 200 years. Recent genetic studies, particularly the platypus whole-genome sequencing project, have revealed the molecular basis of some of the extraordinary characteristics of monotremes. This and other works demonstrate the great value of research on our most distantly related mammalian relatives for comparative genomics and developmental biology. In this review we focus on the reproductive biology of monotremes and discuss works that unravel genes involved in lactation, testicular descent, gamete biology and fertilization, and early development. In addition we discuss works on the evolution of the complex sex chromosome system in platypus and echidna, which has also significant impact on our general understanding of mammalian sex chromosomes and sex determination.

© 2008 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Review Article

Received: May 07, 2008
Accepted: June 09, 2008
Published online: September 03, 2008
Issue release date: September 2008

Number of Print Pages: 13
Number of Figures: 6
Number of Tables: 0

ISSN: 1661-5425 (Print)
eISSN: 1661-5433 (Online)

For additional information: https://www.karger.com/SXD


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