Cells Tissues Organs
Original Paper
Ultrastructural and Morphometric Study of Hepatocytes from Near-Term Minipig Fetuses Exposed to Ethanol in vivoRømert P. · Matthiessen M.E.Anatomy Departments C and A, University of Copenhagen, Denmark
Keywords: EthanolFetusHepatocyteMinipigMorphometry |
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Article / Publication Details
Received: September 01, 1991
Accepted: November 07, 1991
Published online: July 16, 2008
Issue release date: 1992
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 1422-6405 (Print)
eISSN: 1422-6421 (Online)
For additional information: https://www.karger.com/CTO
Abstract
Hepatocytes of near-term minipig fetuses were studied after their mothers had received a daily addition of 3 g/kg body weight of ethanol to the ordinary sufficient fodder during the last half of pregnancy. The ethanol-exposed hepatocytes were evaluated ultrastructurally and morphometrically, and compared with hepatocytes of unexposed fetuses. The present results show that hepatocytes of near-term fetuses, exposed to a high concentration of ethanol for a long period exhibit neither qualitative nor quantitative changes. This is in contrast to maternal hepatocytes which show an adaptation of cellular components to ethanol by developing increased volume densities of mitochondria and smooth endoplas-mic reticulum and a decreased volume density of glycogen.
© 1992 S. Karger AG, Basel
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Article / Publication Details
Received: September 01, 1991
Accepted: November 07, 1991
Published online: July 16, 2008
Issue release date: 1992
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 1422-6405 (Print)
eISSN: 1422-6421 (Online)
For additional information: https://www.karger.com/CTO
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