Cells Tissues Organs
Original Paper
Lymphoid Tissue Changes during Early Syngeneic Pregnancy in theRT1u RatHabbal O.a · McLean J.baDepartment of Human and Clinical Anatomy, College of Medicine, Sultan Qaboos University, Muscat, Sultanate of Oman; bDepartment of Cell and Structural Biology, Medical School, University of Manchester, UK
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Article / Publication Details
Received: January 23, 1992
Accepted: March 03, 1992
Published online: July 16, 2008
Issue release date: 1992
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 1422-6405 (Print)
eISSN: 1422-6421 (Online)
For additional information: https://www.karger.com/CTO
Abstract
An active immunological response by the female to mating and pregnancy is important, if not essential, to successful reproduction. Alloantigens which have been demonstrated on spermatozoa include histocompatibility antigens. In the enigmatic success of the fetal allograft, the conceptus survives owing to failure of the mother either to initiate or complete the process of rejection. In this study, AO(RT1u/AgB2) female rats were caged with male rats of the same strain. Observations were obtained from the first 5 days of their postcoital period, identifying lymphoid tissue changes which are due to the presence of the ejaculate and early products of conception in the female reproductive tract. A significant increase in intrathymic proliferation by day 3 is thought to be a hormonal effect induced by the cervical stimulation at mating. The postcoital exodus of lymphocytes from the thymus is possibly in response to coitus and induced by the seminal plasma to safeguard the implanting conceptus.
© 1992 S. Karger AG, Basel
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Article / Publication Details
Received: January 23, 1992
Accepted: March 03, 1992
Published online: July 16, 2008
Issue release date: 1992
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 1422-6405 (Print)
eISSN: 1422-6421 (Online)
For additional information: https://www.karger.com/CTO
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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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